10967/191 - QDB Compounds

QsarDB Repository

Kidron, H.; Vellonen, K.-S.; del Amo, E. M.; Tissari, A.; Urtti, A. Prediction of the Corneal Permeability of Drug-Like Compounds. Pharm. Res. 2010, 27, 1398–1407.

69 compounds | Property logPapp: The logarithm of the corneal permeability [log(cm/s)]

IDNamelogPappRefDetails
1Acetazolamide-6.04[1,2]View
2Alprenolol-4.54[3]View
3Atenolol-6.17[4]View
4Benzolamide-6.85[1]View
5Bevantolol-4.27[4]View
6N-bromoacetazolamide-6.42[1]View
7Bufuralol-4.24[4]View
8Chlorzolamide-4.74[1]View
9Clonidine-4.51[3,5]View
10Corynanthine-4.96[5]View
11Cyclophosphamide-4.96[6]View
12Ethoxazolamide-4.25[1]View
132-benzothiazolesulfonamide-4.44[7]View
146-hydroxy-2-benzo-thiazolesulfonamide-5.25[7]View
156-chloro-2-benzo-thiazolesulfonamide-4.37[7]View
164,6-dichloro-2-benzo-thiazolesulfonamide-4.41[7]View
176-amino-2-benzo-thiazolesulfonamide-5.17[7]View
186-nitro-2-benzo-thiazolesulfonamide-5.18[7]View
196-hydroxyethoxy-2-benzothiazolesulfonamide-5.82[7]View
206-benzyloxy-2-benzo-thiazolesulfonamide-4.33[7]View
216-acetamido-2-benzo-thiazolesulfonamide-5.33[7]View
22Levobunolol-4.7[3,4]View
23Labetalol-4.85[3]View
24Methazolamide-5.59[1]View
255-imino-4-methyl-1,3,4-thiadiazoline-2-sulfonamide-6.11[1]View
26Metoprolol-4.6[3,4]View
27Nadolol-6[4]View
28Oxprenolol-4.54[3,4]View
29Penbutolol-4.35[4]View
30Phenylephrine-6.03[5]View
31Pindolol-5[3]View
32Propranolol-4.32[4]View
33Rauwolfine-5.04[5]View
346H,7H,8H,9H-[1,2,3]thiadiazolo[5,4-h]isoquinoline i-4.1[5]View
35Benalfocin i-4.15[5]View
365,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline i-4.31[5]View
37Sotalol-5.8[4]View
381[(N-methylamino) sulfonyl]-4-chloro-benzene-4.19[2]View
394-chlorobenzene-1-sulfonamide-4.26[2]View
40(3Z)-3-(phenylimino)-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.1[8]View
41(3Z)-3-[(3-chlorophenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-4.89[8]View
42(3Z)-3-[(4-chlorophenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.08[8]View
43(3Z)-3-[(3-methoxyphenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.35[8]View
44(3Z)-3-[(4-methoxyphenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.28[8]View
45(3Z)-3-[(4-hydroxyphenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-6.46[8]View
46(3Z)-3-[(3-fluorophenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.19[8]View
47(3Z)-3-[(4-fluorophenyl)imino]-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.39[8]View
48(3Z)-3-{[4-(dimethylamino)phenyl]imino}-[1,2,4]thiadiazolo[3,4-b][1,3,4]thiadiazole-6-sulfonamide i-5.24[8]View
49Timolol-4.92[3,4]View
50Trichlormethazolamide-4.96[1,9]View
51Trifluormethazolamide-5.41[1]View
52Yohimbine-4.74[5]View
53Cinoxacin-5.82[10]View
54Nalidixic acid-4.77[10]View
55Enoxacin-5.77[10]View
56Norfloxacin-5.85[10]View
57Ofloxacin-5.72[10]View
58Ciprofloxacin-5.89[10]View
59Moxifloxacin-5.04[11]View
60Levofloxacin-5.54[11]View
61Gatifloxacin-5.6[11]View
62Lomefloxacin-5.46[11]View
63Buspirone-4.18[11]View
64Apraclonidine-5.42[11]View
65Fluorescein-4.8[11]View
66Pilocarpine-5.01[11]View
67Nepafenac-4.13[11]View
68Betaxolol-4.22[11]View
69Dexamethasone-5.04[11]View

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