Kidron, H.; Vellonen, K.-S.; del Amo, E. M.; Tissari, A.; Urtti, A. Prediction of the Corneal Permeability of Drug-Like Compounds. Pharm. Res. 2010, 27, 1398–1407.
Compound
| ID: | 9 | |
|---|---|---|
| Name: | Clonidine | |
| Description: | ||
| Labels: | ||
| CAS: | ||
| InChi Code: | InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) |
Properties
perm: Corneal permeability [cm/s]
| Value | Source or prediction |
|---|---|
| 3.1E-5 |
experimental value |
logPapp: The logarithm of the corneal permeability [log(cm/s)]
| Value | Source or prediction |
|---|---|
| -4.51 |
experimental value |
| -4.5 |
Eq.3b: Model for drug-like compounds at pH 7.4 (Trainig set) |
| -4.49 |
Eq.4b: Model for drug-like compounds at pH 8.0 (Trainig set) |
Links to External Resources
| Link | Resource description |
|---|---|
| DTXSID6022846 | US EPA CompTox Dashboard |