Kidron, H.; Vellonen, K.-S.; del Amo, E. M.; Tissari, A.; Urtti, A. Prediction of the Corneal Permeability of Drug-Like Compounds. Pharm. Res. 2010, 27, 1398–1407.
Compound
| ID: | 1 | |
|---|---|---|
| Name: | Acetazolamide | |
| Description: | ||
| Labels: | ||
| CAS: | ||
| InChi Code: | InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) |
Properties
perm: Corneal permeability [cm/s]
| Value | Source or prediction |
|---|---|
| 9.1E-7 |
experimental value |
logPapp: The logarithm of the corneal permeability [log(cm/s)]
| Value | Source or prediction |
|---|---|
| -6.04 |
experimental value |
| -5.87 |
Eq.3b: Model for drug-like compounds at pH 7.4 (Trainig set) |
| -5.94 |
Eq.4b: Model for drug-like compounds at pH 8.0 (Trainig set) |
Links to External Resources
| Link | Resource description |
|---|---|
| DTXSID7022544 | US EPA CompTox Dashboard |