New community from Italy (JRC)

In 2020, the QsarDB team celebrated Europe Day (May 9) in a modest but professional way. Namely, on that day, a new community was opened for the European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM), which is a part of the European Commission's Joint Research Center (JRC) in Ispra, Italy.

European Commission

The JRC conducts research to provide independent scientific advice and support to EU policies. EURL ECVAM promotes the replacement, reduction and refinement of animal procedures (three Rs). Alternatives to animal testing in toxicology include computational methods such as quantitative structure-activity relationship (QSAR) models.

The EURL ECVAM at JRC is an active developer of QSAR models, studied the use of the models in regulatory applications and maintained the JRC QSAR model database. In 2020, the JRC QSAR model database ceased operations and the datasets were archived with 154 QSAR Model Reporting Format (QMRF) documents and data. The QsarDB team has digitized the first QSAR models from the JRC database already in 2015-2016. A significant number of models have now been added, and in total around 25% of the JRC QSAR model database has been digitized and added to the repository. It has to be said that only those QSAR models that have enough raw data in the original research article or in the QMRF can be digitized.

If the model submitted to the JRC's QSAR model database is not listed in QsarDB and you can provide necessary raw data, please contact the QsarDB team ( to implement the model in the repository.

Your QsarDB team.

EURL ECVAM community HDL is: 10967/232

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