Abstract: Twenty-nine compounds, including amino and nitro derivatives of aromatic hydrocarbons as well as azaarenes and indole analogs, were assayed. The biological activity was monitored as population growth to axenic cultures of the ciliate Tetrahymena pyriformis. Structure-activity relationships were examined by linear regression analysis of log biological activity ...

Abstract: The relative toxicity of 14 normal aliphatic alcohols has been determined as 48-hr 50% population growth inhibition (log BR, biological response) of Tetrahymena pyriformis. A linear relationship was observed between log BR and the 1-octanol/water partition coefficient (log Kow). Comparison of log BR with 96-hr 50% mortality data for Pimephales promelas revealed ...

Abstract: Twenty-two four-position derivatives of pyridine (C5H5N) were tested following an acute static regime with biological response being monitored as population growth of Tetrahymena pyriformis. The vinyl derivative was the most active and the hydroxy derivative was the least active. Structure-activity relationships were examined using substituent constants as ...