HumanHealth
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Ringeissen, S.; Marrot, L.; Note, R.; Labarussiat, A.; Imbert, S.; Todorov, M.; Mekenyan, O.; Meunier, J.-R. Development of a mechanistic SAR model for the detection of phototoxic chemicals and use in an integrated testing strategy. Toxicol. In Vitro 2011, 25, 324–334.
Published: Alfonso T. Garcia-Sosa (2015-03-17)
Abstract: Phototoxicity is of increasing concern in dermatology, since modern lifestyle is often associated with exposure to sunlight. The most commonly reported process is via oxidative reactions. Therefore characterizing the ‘‘photo-pro-oxidant” potential of a compound early in its industrial development is of utmost interest, especially for compounds likely to undergo ...