Abstract: The relative biological response (log BR) for each of 30 select substituted phenols and anilines was evaluated using the 48-h Tetrahymena pyriformis population growth test system. Simple linear regression analysis of log BR versus log Kow (1-octanol/water partition coefficient) was used to formulate a quantitative structure-activity relationship (QSAR). The ...

Abstract: Toxicity data collected in a laboratory setting are the primary source of potency information used for regulatory, modeling, or risk assessment purposes. However, the relative reproducibility of such toxicity data is rarely discussed. This study investigated the reproducibility of growth impairment data for the freshwater ciliate Tetrahymena pyriformis exposed ...