Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009.
QDB archive DOI: 10.15152/QDB.221 DOWNLOAD
QsarDB content
Property pLC50: 96-h Fathead minnow toxicity as log(1/LC50) [-log(mol/L)]
QSAR: Polar narcosis
Regression model (regression) QMRF
Open in:QDB ExplorerQDB Predictor
| Name | Type | n |
R2 |
σ |
|---|---|---|---|---|
| Training set | training | 43 | 0.719 | 0.475 |
Citing
When using this QDB archive, please cite (see details) it together with the original article:
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Piir, G. Data for: Polar narcosis QSAR for fathead minnow acute toxicity. QsarDB repository, QDB.221. 2020. https://doi.org/10.15152/QDB.221
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Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009. http://data.europa.eu/89h/e4ef8d13-d743-4524-a6eb-80e18b58cba4
Metadata
| dc.date.accessioned | 2020-03-13T10:09:05Z | |
| dc.date.available | 2020-03-13T10:09:05Z | |
| dc.date.issued | 2020-03-13 | |
| dc.identifier.uri | http://hdl.handle.net/10967/221 | |
| dc.identifier.uri | http://dx.doi.org/10.15152/QDB.221 | |
| dc.description.abstract | All compounds are considered to act by polar narcosis. This is well established for non-reactive compounds. Acute lethality is brought about by accumulation in cellular membranes causing their disruption and ultimately death of the organism. The ability of the compound to accumulate in a cellular membrane is thought to be related to its intrinsic hydrophobicity. Hydrophobicity of these compounds is modelled by log P. | |
| dc.publisher | Geven Piir | |
| dc.rights | Attribution 4.0 International | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
| dc.title | Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009. | |
| qdb.property.endpoint | 3. Ecotoxic effects 3.3. Acute toxicity to fish | en_US |
| qdb.property.species | Pimephales promelas (Fathead minnow) | en_US |
| qdb.descriptor.application | KOWWIN 1.67 | en_US |
| bibtex.entry | techreport | en_US |
| bibtex.entry.author | Bajot, F. | |
| bibtex.entry.author | Cronin, M. | |
| bibtex.entry.institution | Liverpool John Moores University | en_US |
| bibtex.entry.number | Q17-33-0032 | en_US |
| bibtex.entry.title | Polar narcosis QSAR for fathead minnow acute toxicity | en_US |
| bibtex.entry.url | http://data.europa.eu/89h/e4ef8d13-d743-4524-a6eb-80e18b58cba4 | |
| bibtex.entry.year | 2009 | |
| qdb.model.type | Regression model (regression) | en_US |
| qdb.model.qmrf | QSAR=Q17-33-0032 | en_US |
Files in this item
| Name | Description | Format | Size | View |
|---|---|---|---|---|
| Q17-33-0032.qdb.zip | Model for fish toxicity | application/zip | 6.442Kb | View/ |
| Q17-33-0032.pdf | QMRF | 33.17Kb | View/ |
Files associated with this item are distributed
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under Creative Commons license.
This item appears in the following Collection(s)
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JRC QSAR Model Database models and data
European Union Reference Laboratory for Alternatives to Animal Testing, JRC (Italy) -
Original publications
Liverpool John Moores University (England), Chemoinformatics Research Group