Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009.

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Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009.

QDB archive DOI: 10.15152/QDB.221   DOWNLOAD

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Property pLC50: 96-h Fathead minnow toxicity as log(1/LC50) [-log(mol/L)]

QSAR: Polar narcosis

Regression model (regression)   QMRF

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Title: Bajot, F.; Cronin, M. Polar narcosis QSAR for fathead minnow acute toxicity. Q17-33-0032. Liverpool John Moores University, 2009.
Abstract:All compounds are considered to act by polar narcosis. This is well established for non-reactive compounds. Acute lethality is brought about by accumulation in cellular membranes causing their disruption and ultimately death of the organism. The ability of the compound to accumulate in a cellular membrane is thought to be related to its intrinsic hydrophobicity. Hydrophobicity of these compounds is modelled by log P.
URI:http://hdl.handle.net/10967/221
http://dx.doi.org/10.15152/QDB.221
Date:2020-03-13


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