Netzeva, T.I.; Aptula, A.O.; Chaudary, S.H.; Duffy, J.C.; Schultz, T.W.; Schüürmann, G.; Cronin, M.T.D. Structure-Activity Relationships for the Toxicity of Substituted Poly-hydroxylated Benzenes to Tetrahymena pyriformis: Influence of Free Radical Formation. QSAR Comb. Sci. 2003, 22, 6, 575–582.

30 compounds | Property pIGC50: 40-h Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

ID	Name	pIGC50	Details
1	Hydroquinone	0.473	View
2	Methylhydroquinone	1.858	View
3	2,3-dimethylhydroquinone	1.413	View
4	Trimethylhydroquinone	1.342	View
5	Tetramethylhydroquinone	1.281	View
6	Methoxyhydroquinone	2.202	View
7	Phenylhydroquinone	2.005	View
8	Chlorohydroquinone	1.262	View
9	Bromohydroquinone	1.678	View
10	Tetrafluorohydroquinone	1.844	View
11	Tetrachlorohydroquinone	2.109	View
12	Catechol	0.752	View
13	Resorscinol	-0.652	View
14	1,3,5-trihydroxybenzene	-1.264	View
15	1,2,4-trihydroxybenzene	0.439	View
16	1,2,3-trihydroxybenzene	0.850	View
17	5-methylresorcinol	-0.389	View
18	5-pentylresorcinol	1.306	View
19	4-hexylresorcinol	1.798	View
20	2-nitroresorcinol	0.658	View
21	4-chlororesorcinol	0.125	View
22	4,6-dichlororesorcinol	0.967	View
23	2,4,6-tribromoresorcinol	1.060	View
24	3-methylcatechol	0.280	View
25	4-methylcatechol	0.368	View
26	3,5-di(tert)butylcatechol	2.109	View
27	4-nitrocatechol	1.170	View
28	4-chlorocatechol	1.061	View
29	Tetrachlorocatechol	1.697	View
30	Tetrabromocatechol	0.984	View

Bibliography

Netzeva, T. I.; Aptula, A. O.; Chaudary, S. H.; Duffy, J. C.; Schultz, T. W.; Schüürmann, G.; Cronin, M. T. D. Structure-Activity Relationships for the Toxicity of Substituted Poly-hydroxylated Benzenes to Tetrahymena pyriformis: Influence of Free Radical Formation. QSAR Comb. Sci. 2003, 22, 575–582. https://doi.org/10.1002/qsar.200330816
Schultz, T. W. TETRATOX: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. Toxicol. Mech. Meth. 1997, 7, 289–309. https://doi.org/10.1080/105172397243079