198 compounds | Property MOA: Mode of action
ID | Name | MOA | Details |
---|---|---|---|
1 | 2,4-dimethylphenol | Polar narcotic (zone 1) | View |
2 | 4-methylphenol | Polar narcotic (zone 1) | View |
3 | 3-methylphenol | Polar narcotic (zone 1) | View |
4 | 3,5-dimethylphenol | Polar narcotic (zone 1) | View |
5 | phenol | Polar narcotic (zone 1) | View |
6 | 4-butoxyphenol | Polar narcotic (zone 1) | View |
7 | 4-ethylphenol | Polar narcotic (zone 1) | View |
8 | 3-methoxyphenol | Polar narcotic (zone 1) | View |
9 | 4-methoxyphenol | Polar narcotic (zone 1) | View |
10 | 2-allylphenol | Polar narcotic (zone 1) | View |
11 | 2,3,6-trimethylphenol | Polar narcotic (zone 1) | View |
12 | 2-hydroxy-4,5-dimethylacetophenone | Polar narcotic (zone 1) | View |
13 | 3,5-dimethoxyphenol | Polar narcotic (zone 1) | View |
14 | 4-hydroxyphenethylalcohol | Polar narcotic (zone 1) | View |
15 | 2,3-dimethylphenol | Polar narcotic (zone 1) | View |
16 | 3,4,5-trimethylphenol | Polar narcotic (zone 1) | View |
17 | 2,4,6-trimethylphenol | Polar narcotic (zone 1) | View |
18 | 3-tert-butylphenol | Polar narcotic (zone 1) | View |
19 | 3-isopropylphenol | Polar narcotic (zone 1) | View |
20 | 3-ethylphenol | Polar narcotic (zone 1) | View |
21 | 3-hydroxybenzylalcohol | Polar narcotic (zone 1) | View |
22 | 3-acetamidophenol | Polar narcotic (zone 1) | View |
23 | 4-ethoxyphenol | Polar narcotic (zone 1) | View |
24 | 4-propylphenol | Polar narcotic (zone 1) | View |
25 | 3-ethoxy-4-methoxyphenol | Polar narcotic (zone 1) | View |
26 | 2,3,5-trimethylphenol | Polar narcotic (zone 1) | View |
27 | 2-tert-butylphenol | Polar narcotic (zone 1) | View |
28 | 2-isopropylphenol | Polar narcotic (zone 1) | View |
29 | 2-ethylphenol | Polar narcotic (zone 1) | View |
30 | 2-hydroxybenzylalcohol | Polar narcotic (zone 1) | View |
31 | 2-methoxyphenol | Polar narcotic (zone 1) | View |
32 | 2,6-dimethoxyphenol | Polar narcotic (zone 1) | View |
33 | 2-ethoxyphenol | Polar narcotic (zone 1) | View |
34 | 2-methylphenol | Polar narcotic (zone 1) | View |
35 | 3,4-dimethylphenol | Polar narcotic (zone 1) | View |
36 | 2,5-dimethylphenol | Polar narcotic (zone 1) | View |
37 | 4-(tert-)butylphenol | Polar narcotic (zone 1) | View |
38 | 4-sec-butylphenol | Polar narcotic (zone 1) | View |
39 | 4-isopropylphenol | Polar narcotic (zone 1) | View |
40 | 4-hydroxy-3-methoxyphenethylalcohol | Polar narcotic (zone 1) | View |
41 | 3-hydroxy-4-methoxybenzylalcohol | Polar narcotic (zone 1) | View |
42 | 4-hydroxy-3-methoxybenzylalcohol | Polar narcotic (zone 1) | View |
43 | 4-hydroxy-3-methoxybenzylamine | Polar narcotic (zone 1) | View |
44 | 2,4,6-tris(dimethylaminomethyl)phenol | Polar narcotic (zone 1) | View |
45 | 4-allyl-2-methoxyphenol | Polar narcotic (zone 1) | View |
46 | resorscinol | Polar narcotic (zone 1) | View |
47 | 1,3,5-trihydroxybenzene | Polar narcotic (zone 1) | View |
48 | 4-hexylresorcinol | Polar narcotic (zone 1) | View |
49 | 5-methylresorcinol | Polar narcotic (zone 1) | View |
50 | 5-pentyresorcinol | Polar narcotic (zone 1) | View |
51 | 4-benzyloxyphenol | Polar narcotic (zone 1) | View |
52 | 4-chloro-2-methylphenol | Polar narcotic (zone 1) | View |
53 | 4-chloro-3-methylphenol | Polar narcotic (zone 1) | View |
54 | 4-chloro-3,5-dimethylphenol | Polar narcotic (zone 1) | View |
55 | 4-bromophenol | Polar narcotic (zone 2) | View |
56 | 4-chlorophenol | Polar narcotic (zone 2) | View |
57 | 3-chlorophenol | Polar narcotic (zone 2) | View |
58 | 2-chloro-4,5-dimethylphenol | Polar narcotic (zone 2) | View |
59 | 4-hydroxybenzylcyanide | Polar narcotic (zone 2) | View |
60 | 2-fluorophenol | Polar narcotic (zone 2) | View |
61 | 4-fluorophenol | Polar narcotic (zone 2) | View |
62 | 3-fluorophenol | Polar narcotic (zone 2) | View |
63 | 4-iodophenol | Polar narcotic (zone 2) | View |
64 | 3-bromophenol | Polar narcotic (zone 2) | View |
65 | 2-chloro-5-methylphenol | Polar narcotic (zone 2) | View |
66 | 3-iodophenol | Polar narcotic (zone 2) | View |
67 | 3-chloro-5-methoxyphenol | Polar narcotic (zone 2) | View |
68 | 2-bromo-4-methylphenol | Polar narcotic (zone 2) | View |
69 | 2-bromophenol | Polar narcotic (zone 2) | View |
70 | 2-chlorophenol | Polar narcotic (zone 2) | View |
71 | ethyl-4-hydroxy-3-methoxyphenylacetate | Polar narcotic (zone 2) | View |
72 | 2-methoxy-4-propenylphenol | Polar narcotic (zone 2) | View |
73 | 4-chlororesorcinol | Polar narcotic (zone 2) | View |
74 | 2-phenylphenol | Polar narcotic (zone 2) | View |
75 | 4-phenylphenol | Polar narcotic (zone 2) | View |
76 | 5-bromo-2--hydroxybenzylalcohol | Polar narcotic (zone 3) | View |
77 | 3-hydroxybenzaldehyde | Polar narcotic (zone 3) | View |
78 | 2-hydroxyacetophenone | Polar narcotic (zone 3) | View |
79 | ethyl-4-hydroxybenzoate | Polar narcotic (zone 3) | View |
80 | 2,4-dichlorophenol | Polar narcotic (zone 3) | View |
81 | 3-ethoxy-4-hydroxybenzaldehyde | Polar narcotic (zone 3) | View |
82 | 3-methoxy4-hydroxybenzaldehyde | Polar narcotic (zone 3) | View |
83 | 3-hydroxyacetophenone | Polar narcotic (zone 3) | View |
84 | 4-hydroxybenzaldehyde | Polar narcotic (zone 3) | View |
85 | syringaldehyde | Polar narcotic (zone 3) | View |
86 | 3-methoxysalicylaldehyde | Polar narcotic (zone 3) | View |
87 | methyl-3-hydroxybenzoate | Polar narcotic (zone 3) | View |
88 | 3-chloro-4-fluorophenol | Polar narcotic (zone 3) | View |
89 | 2,6-difluorophenol | Polar narcotic (zone 3) | View |
90 | 5-bromovanillin | Polar narcotic (zone 3) | View |
91 | 2,4-difluorophenol | Polar narcotic (zone 3) | View |
92 | 2,6-dichloro-4-fluorophenol | Polar narcotic (zone 3) | View |
93 | α,α,α-trifluoro-4-cresol | Polar narcotic (zone 3) | View |
94 | 2,3-dichlorophenol | Polar narcotic (zone 3) | View |
95 | 2,5-dichlorophenol | Polar narcotic (zone 3) | View |
96 | 3,5-dichlorophenol | Polar narcotic (zone 3) | View |
97 | 2-cyanophenol | Polar narcotic (zone 3) | View |
98 | 2,4-dibromophenol | Polar narcotic (zone 3) | View |
99 | 4-hydroxybenzamide | Polar narcotic (zone 3) | View |
100 | 3-hydroxy-4-methoxybenzaldehyde | Polar narcotic (zone 3) | View |
101 | 2-hydroxybenzamide | Polar narcotic (zone 3) | View |
102 | salicylic acid | Polar narcotic (zone 3) | View |
103 | 4-hydroxypropiophenone | Polar narcotic (zone 3) | View |
104 | 4-cyanophenol | Polar narcotic (zone 3) | View |
105 | ethyl-3-hydroxybenzoate | Polar narcotic (zone 3) | View |
106 | 2,6-dichlorophenol | Polar narcotic (zone 3) | View |
107 | 3-cyanophenol | Polar narcotic (zone 3) | View |
108 | 2,4,6-trichlorophenol | Polar narcotic (zone 3) | View |
109 | salicylhydroxamicacid | Polar narcotic (zone 3) | View |
110 | 2-hydroxybenzaldehyde | Polar narcotic (zone 3) | View |
111 | 3,5-dibromosalicylaldehyde | Polar narcotic (zone 3) | View |
112 | salicylhydrazide | Polar narcotic (zone 3) | View |
113 | salicylaldoxime | Polar narcotic (zone 3) | View |
114 | 3,4-dichlorophenol | Polar narcotic (zone 3) | View |
115 | 3-amino-4-hydroxybenzenesulfonic acid | Polar narcotic (zone 3) | View |
116 | 3-hydroxybenzoicacid | Polar narcotic (zone 3) | View |
117 | methyl-4-hydroxybenzoate | Polar narcotic (zone 3) | View |
118 | 4-hydroxyacetophenone | Polar narcotic (zone 3) | View |
119 | 4-hydroxybenzoic acid | Polar narcotic (zone 3) | View |
120 | 4-hydroxy-3-methoxyacetophenone | Polar narcotic (zone 3) | View |
121 | 2-hydroxy-4-methoxyacetophenone | Polar narcotic (zone 3) | View |
122 | 3,5-dichlorosalicyaldehyde | Polar narcotic (zone 3) | View |
123 | 5-fluoro-2-hydroxyacetophenone | Polar narcotic (zone 3) | View |
124 | 2-hydroxy-5-methylacetophenone | Polar narcotic (zone 3) | View |
125 | 4-hydroxy-3-methoxybenzonitrile | Polar narcotic (zone 3) | View |
126 | 4-hydroxy-2-methylacetophenone | Polar narcotic (zone 3) | View |
127 | methyl-4-methoxysalicylate | Polar narcotic (zone 3) | View |
128 | 2-hydroxethylsalicylate | Polar narcotic (zone 3) | View |
129 | 4-hydroxyphenylaceticacid | Polar narcotic (zone 3) | View |
130 | 4,6-dichlororesorcinol | Polar narcotic (zone 3) | View |
131 | 4-hydroxybenzophenone | Polar narcotic (zone 3) | View |
132 | 3-phenylphenol | Polar narcotic (zone 3) | View |
133 | 2,5-dinitrophenol | Respiratory uncoupler | View |
134 | 2,4-dinitrophenol | Respiratory uncoupler | View |
135 | 4,6-dinitro-2-methylphenol | Respiratory uncoupler | View |
136 | 2,6-dinitrophenol | Respiratory uncoupler | View |
137 | 3,4-dinitrophenol | Respiratory uncoupler | View |
138 | 2,4-chloro-6-nitrophenol | Respiratory uncoupler | View |
139 | 2,6-dinitro-4-cresol | Respiratory uncoupler | View |
140 | 2,6-dichloro-4-nitrophenol | Respiratory uncoupler | View |
141 | 2,3-dinitrophenol | Respiratory uncoupler | View |
142 | 2,3,5,6-tetrafluorophenol | Respiratory uncoupler | View |
143 | pentafluorophenol | Respiratory uncoupler | View |
144 | 2,4,6-nitrophenol | Respiratory uncoupler | View |
145 | 2,6-bromo-4-nitrophenol | Respiratory uncoupler | View |
146 | 2,3-dicyanohydroquinone | Respiratory uncoupler | View |
147 | 4-acetamidophenol | Pro-electrophile | View |
148 | 2-amino-4-(tert-)butylphenol | Pro-electrophile | View |
149 | 4-aminophenol | Pro-electrophile | View |
150 | 2,4-diaminophenol | Pro-electrophile | View |
151 | 5-amino-2-methoxyphenol | Pro-electrophile | View |
152 | 4-amino-2-methylphenol | Pro-electrophile | View |
153 | 6-amino-2,4-dimethylphenol | Pro-electrophile | View |
154 | 3-aminophenol | Pro-electrophile | View |
155 | 2-aminophenol | Pro-electrophile | View |
156 | 5-chloro-2-hydroxyaniline | Pro-electrophile | View |
157 | 4-amino-2,3-dimethylphenol | Pro-electrophile | View |
158 | 5-amino-2-methoxyphenol | Pro-electrophile | View |
159 | hydroquinone | Pro-electrophile | View |
160 | methylhydroquinone | Pro-electrophile | View |
161 | 2,3-dimethylhydroquinone | Pro-electrophile | View |
162 | trimethylhydroquinone | Pro-electrophile | View |
163 | chlorohydroquinone | Pro-electrophile | View |
164 | bromohydroquinone | Pro-electrophile | View |
165 | phenylhydroquinone | Pro-electrophile | View |
166 | methoxyhydroquinone | Pro-electrophile | View |
167 | catechol | Pro-electrophile | View |
168 | 1,2,4-trihydroxybenzene | Pro-electrophile | View |
169 | 1,2,3-trihydroxybenzene | Pro-electrophile | View |
170 | 3-methylcatechol | Pro-electrophile | View |
171 | 4-methylcatechol | Pro-electrophile | View |
172 | 4-chlorocatechol | Pro-electrophile | View |
173 | 4-nitrophenol | Soft electrophile | View |
174 | 4-nitrosophenol | Soft electrophile | View |
175 | 4-methyl-2-nitrophenol | Soft electrophile | View |
176 | 4-amino-2-nitrophenol | Soft electrophile | View |
177 | 4-methyl-3-nitrophenol | Soft electrophile | View |
178 | 3-methyl-4-nitrophenol | Soft electrophile | View |
179 | 2-chloromethyl-4-nitrophenol | Soft electrophile | View |
180 | 5-hydroxy-2-nitrobenzaldehyde | Soft electrophile | View |
181 | 5-fluoro-2-nitrophenol | Soft electrophile | View |
182 | 3-nitrophenol | Soft electrophile | View |
183 | 2-chloro-4-nitrophenol | Soft electrophile | View |
184 | 2-amino-4-chloro-5-nitrophenol | Soft electrophile | View |
185 | 4-chloro-6-nitro-3-methylphenol | Soft electrophile | View |
186 | 2-nitrophenol | Soft electrophile | View |
187 | 4-chloro-2-nitrophenol | Soft electrophile | View |
188 | 2-amino-4-nitrophenol | Soft electrophile | View |
189 | 3-hydroxy-4-nitrobenzaldehyde | Soft electrophile | View |
190 | 4-hydroxy-3-nitrobenzaldehyde | Soft electrophile | View |
191 | 5-hydroxy-2-nitrobenzaldehyde | Soft electrophile | View |
192 | 3-fluoro-4-nitrophenol | Soft electrophile | View |
193 | 4-nitro-3-(trifluoromethyl)-phenol | Soft electrophile | View |
194 | 4-nitrocatechol | Soft electrophile | View |
195 | 2-nitroresorcinol | Soft electrophile | View |
196 | tetramethylhydroquinone | Pro-redox cycler | View |
197 | tetrachlorohydroquinone | Pro-redox cycler | View |
198 | tetrafluorohydroquinone | Pro-redox cycler | View |
Schultz, T. W.; Sinks, G. D.; Cronin, M. T. D. Identification of Mechanisms of Toxic Action of Phenols to Tetrahymena pyriformis from Molecular Descriptors. In Quantitative Structure-Activity Relationships in Environmental Sciences; Chen, F.; Schüürmann, G., Eds.; SETAC Press; 1997.