Bearden, A.P.; Schultz, T.W. Structure-Activity Relationships for Pimephales and Tetrahymena: a Mechanism of Action Approach. Environ. Toxicol. Chem. 1997, 16, 6, 1311–1317.

Compound

	ID:	45
	Name:	α,α,α-4-Tetrafluoro-3-toluidine
	Description:
	Labels:
	CAS:	2357-47-3
	InChi Code:

Properties

pLC50: 96-h Fathead minnow toxicity as log(1/LC50) [log(L/mmol)]

Value	Source or prediction
0.77	experimental value
1.00	4: Polar narcosis (Training)
1.04	6: Polar narcosis (phenols) (Training)
1.11	17: Nonpolar narcosis (phenols) (Training)

pIGC50: 2-day Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

Value	Source or prediction
0.77	experimental value
0.50	3: Polar narcosis (Training)
0.43	5: Polar narcosis (phenols) (Training)
0.95	15: Nonpolar narcosis (Training)
1.22	16: Nonpolar narcosis (phenols) (Training)

MOA: Mode of action

Value	Source or prediction
Phenol polar narcotic	experimental value