Yarbrough, J.W.; Schultz, T.W. Abiotic Sulfhydryl Reactivity: A Predictor of Aquatic Toxicity for Carbonyl-Containing α,β-Unsaturated Compounds. Chem. Res. Toxicol. 2007, 20, 3, 558–562.

44 compounds | Property IGC50: 40-h Tetrahymena toxicity as IGC50 [mmol/L]

ID	Name	IGC50	Ref	Details
1	acrolein	0.013	[1]	View
2	methyl acrylate	0.28	[1]	View
3	ethyl acrylate	0.31	[2]	View
4	vinyl acrylate	0.038	[1]	View
5	n-propyl acrylate	0.3	[2]	View
6	allyl acrylate	0.21	[2]	View
7	propargyl acrylate	0.088	[2]	View
8	n-butyl acrylate	0.3	[2]	View
9	tert-butyl acrylate	4.4	[2]	View
10	n-pentyl acrylate	0.29	[2]	View
11	isopentyl acrylate	0.39	[2]	View
12	methyl methacrylate	22	[1]	View
13	ethyl methacrylate	8.6	[2]	View
14	vinyl methacrylate	4.2	[2]	View
15	n-propyl methacrylate	4.5	[2]	View
16	isopropyl methacrylate	7.6	[2]	View
17	methyl crotonate	8.3	[2]	View
18	ethyl crotonate	5.8	[2]	View
19	vinyl crotonate	1.4	[2]	View
20	methyl tiglate	6.1	[2]	View
21	methyl trans-2-octenoate	0.17	[2]	View
22	methyl propiolate	0.017	[1]	View
23	ethyl propiolate	0.02	[2]	View
24	methyl tetrolate	0.4	[1]	View
25	ethyl tetrolate	0.31	[2]	View
26	methyl 2-octynoate	0.091	[2]	View
27	1-penten-3-one	0.03	[2]	View
28	1-hexen-3-one	0.022	[1]	View
29	1-octen-3-one	0.012	[2]	View
30	3-buten-2-one	0.031	[2]	View
31	3-penten-2-one	0.29	[2]	View
32	4-hexan-3-one	0.12	[1]	View
33	3-octen-2-one	0.18	[2]	View
34	4-methyl-3-penten-2-one	4.4	[2]	View
35	3-methyl-3-penten-2-one	2.2	[2]	View
36	3-butyn-2-one	0.011	[2]	View
37	3-hexyn-2-one	0.048	[1]	View
38	2-butenal	0.088	[1]	View
39	2-pentenal	0.22	[2]	View
40	2-hexenal	0.17	[1]	View
41	2-methyl-2-pentenal	5.8	[1]	View
42	4-methyl-2-pentenal	0.15	[1]	View
43	2,4-hexadienal	0.18	[1]	View
44	2-octenal	0.063	[2]	View

Bibliography

Yarbrough, J. W.; Schultz, T. W. Abiotic Sulfhydryl Reactivity: A Predictor of Aquatic Toxicity for Carbonyl-Containing α,β-Unsaturated Compounds. Chem. Res. Toxicol. 2007, 20, 558–562. https://doi.org/10.1021/tx600344a
Schultz, T. W.; Yarbrough, J. W. Trends in structure-toxicity relationships for carbonyl-containing α,β-unsaturated compounds. SAR QSAR Environ. Res. 2004, 15, 139–146. https://doi.org/10.1080/10629360410001665839
Schultz, T. W. TETRATOX: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. Toxicol. Mech. Meth. 1997, 7, 289–309. https://doi.org/10.1080/105172397243079