46 compounds | Property logIGC50: 48-h Tetrahymena toxicity as log(IGC50) [log(mol/L)]
| ID | Name | logIGC50 | Ref | Details |
|---|---|---|---|---|
| 1 | 2-octynal | -4.72 | [1] | View |
| 2 | phenyl propiolaldehyde | -4.34 | [1] | View |
| 3 | methyl acrolein | -3.67 | [1] | View |
| 4 | 2-ethyl acrolein | -3.91 | View | |
| 5 | trans-2-pentenal | -3.66 | View | |
| 6 | trans-2, cis-6 nonadienal | -4.34 | View | |
| 7 | trans-2-octenal | -4.20 | View | |
| 8 | 4-methyl-2-pentenal | -3.82 | View | |
| 9 | trans-2-decenal | -4.85 | View | |
| 10 | trans,trans-2,4-hexadienal | -3.75 | View | |
| 11 | trans,trans-2,4-heptadienal | -3.86 | View | |
| 12 | trans,trans-2,4-nonadienal | -4.23 | View | |
| 13 | 3-methyl-2-butenal | -3.09 | View | |
| 14 | trans-2-methyl-2-butenal | -2.86 | View | |
| 15 | trans-2-methyl-2-pentenal | -2.98 | View | |
| 16 | 1-pentene-3-one | -4.52 | [1] | View |
| 17 | 1-hexene-3-one | -4.66 | View | |
| 18 | 1-octene-3-one | -4.92 | View | |
| 19 | 3-hexyne-2-one | -4.32 | View | |
| 20 | 3-pentene-2-one | -3.54 | View | |
| 21 | 2-octene-4-one | -4.01 | View | |
| 22 | 2-cyclopentene-1-one | -3.64 | View | |
| 23 | 4-hexene-3-one | -3.93 | View | |
| 24 | 3-heptene-2-one | -3.70 | View | |
| 25 | 3-octene-2-one | -3.74 | View | |
| 26 | 3-nonene-2-one | -3.98 | View | |
| 27 | 3-methyl-3-pentene-2-one | -2.66 | View | |
| 28 | 4-methyl-3-pentene-2-one | -2.36 | View | |
| 29 | 2-methyl-2-cyclopentene-1-one | -2.17 | View | |
| 30 | 3-methyl-2-cyclopentene-1-one | -1.68 | View | |
| 31 | methyl propiolate | -4.77 | View | |
| 32 | ethyl propiolate | -4.70 | View | |
| 33 | propargyl acrylate | -4.06 | View | |
| 34 | allyl acrylate | -3.68 | View | |
| 35 | methyl acrylate | -3.55 | View | |
| 36 | ethyl acrylate | -3.52 | View | |
| 37 | n-propyl acrylate | -3.53 | View | |
| 38 | n-butyl acrylate | -3.52 | View | |
| 39 | tert-butyl acrylate | -3.27 | View | |
| 40 | methyl-trans-2-octenoate | -3.76 | View | |
| 41 | propargyl methacrylate | -2.63 | View | |
| 42 | methyl crotonate | -2.08 | View | |
| 43 | ethyl crotonate | -2.24 | View | |
| 44 | methyl methacrylate | -1.78 | View | |
| 45 | ethyl methacrylate | -2.07 | View | |
| 46 | methyl tiglate | -2.38 | View |
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Schultz, T. W.; Netzeva, T. I.; Roberts, D. W.; Cronin, M. T. D. Structure-Toxicity Relationships for the Effects to Tetrahymena pyriformis of Aliphatic, Carbonyl-Containing, α,β-Unsaturated Chemicals. Chem. Res. Toxicol. 2005, 18, 330–341. http://dx.doi.org/10.1021/tx049833j
Schultz, T. W.; Yarbrough, J. W. Trends in structure-toxicity relationships for carbonyl-containing α,β-unsaturated compounds. SAR QSAR Environ. Res. 2004, 15, 139–146. http://dx.doi.org/10.1080/10629360410001665839
Netzeva, T. I.; Schultz, T. W.; Aptula, A. O.; Cronin, M. T. D. Partial Least Squares Modelling of the Acute Toxicity of Aliphatic Compounds to Tetrahymena pyriformis. SAR QSAR Environ. Res. 2003, 14, 265–283. http://dx.doi.org/10.1080/1062936032000101501
Schultz, T. W. TETRATOX: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. Toxicol. Mech. Meth. 1997, 7, 289–309. http://dx.doi.org/10.1080/105172397243079