HumanHealth
Regression
Schultz, T.W.; Carlson, R.E.; Cronin, M.T.D.; Hermens, J.L.M.; Johnson, R.; O’Brien, P.J.; Roberts, D.W.; Siraki, A.; Wallace, K.B.; Veith, G.D. A conceptual framework for predicting the toxicity of reactive chemicals: modeling soft electrophilicity. SAR QSAR Environ. Res. 2006, 17, 413–428.
Published: Alfonso T. Garcia-Sosa (2015-03-29)
Abstract: Although the literature is replete with QSAR models developed for many toxic effects caused by
reversible chemical interactions, the development of QSARs for the toxic effects of reactive
chemicals lacks a consistent approach. While limitations exit, an appropriate starting-point
for modeling reactive toxicity is the applicability of the general rules of ...