10967/169 - QDB Compounds

QsarDB Repository

Oliveira, K. M. G.; Takahata, Y. QSAR Modeling of Nucleosides Against Amastigotes of Leishmania donovani Using Logistic Regression and Classification Tree. QSAR Comb. Sci. 2008, 27, 1020–1027.

Compound

ID:22
Name:6-amino-1-[(2-hydroxyethoxy)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one
Description:Name and InChI code was generated with JChem for Excel
Labels:
CAS:
InChi Code:InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)3-10-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)

Properties

Activity: Activity against Leishmania donovani

ValueSource or prediction
active

experimental value

active

Eq.3: QSAR model for nucleosides (Validation set)

active

Fig.4: Classification tree for nucleosides (Validation set)