37 compounds | Property logK: Hydrolytic rate constant as logK
| ID | Name | logK | Details |
|---|---|---|---|
| 1 | carbamoylmethyl benzoate i | -1.84 | View |
| 2 | (methylcarbamoyl)methyl benzoate i | -1.93 | View |
| 3 | (ethylcarbamoyl)methyl benzoate i | -1.82 | View |
| 4 | (propylcarbamoyl)methyl benzoate i | -1.72 | View |
| 5 | [(propan-2-yl)carbamoyl]methyl benzoate i | -1.76 | View |
| 6 | (tert-butylcarbamoyl)methyl benzoate i | -1.71 | View |
| 7 | [(carbamoylmethyl)carbamoyl]methyl benzoate i | -1.98 | View |
| 8 | [(1-carbamoylethyl)carbamoyl]methyl benzoate i | -1.81 | View |
| 9 | {[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]carbamoyl}methyl benzoate i | -2 | View |
| 10 | [ethyl(methyl)carbamoyl]methyl benzoate i | -1.28 | View |
| 11 | (diethylcarbamoyl)methyl benzoate i | -1.21 | View |
| 12 | (dipropylcarbamoyl)methyl benzoate i | -1.15 | View |
| 13 | [bis(prop-2-en-1-yl)carbamoyl]methyl benzoate i | -1.26 | View |
| 14 | (dibutylcarbamoyl)methyl benzoate i | -1.05 | View |
| 15 | [bis(2-methylpropyl)carbamoyl]methyl benzoate i | -1.01 | View |
| 16 | [(carbamoylmethyl)(methyl)carbamoyl]methyl benzoate i | -1.37 | View |
| 17 | [(2-hydroxyethyl)(methyl)carbamoyl]methyl benzoate i | -1.21 | View |
| 18 | [ethyl(2-hydroxyethyl)carbamoyl]methyl benzoate i | -1.21 | View |
| 19 | [bis(2-hydroxypropyl)carbamoyl]methyl benzoate i | -1.13 | View |
| 20 | [bis(2-methoxyethyl)carbamoyl]methyl benzoate i | -1.13 | View |
| 21 | ethyl 2-[2-(benzoyloxy)-N-methylacetamido]acetate i | -1.19 | View |
| 22 | [hexyl(methyl)carbamoyl]methyl benzoate i | -1.2 | View |
| 23 | (dihexylcarbamoyl)methyl benzoate i | -1.06 | View |
| 24 | {[2-(dimethylamino)ethyl](methyl)carbamoyl}methyl benzoate i | -1.25 | View |
| 25 | [(pyrrolidin-1-yl)carbamoyl]methyl benzoate i | -1.24 | View |
| 26 | [(piperidin-1-yl)carbamoyl]methyl benzoate i | -1.25 | View |
| 27 | [(azepan-1-yl)carbamoyl]methyl benzoate i | -1.09 | View |
| 28 | [(morpholin-4-yl)carbamoyl]methyl benzoate i | -1.27 | View |
| 29 | [(2-ethylpiperidin-1-yl)carbamoyl]methyl benzoate i | -1.08 | View |
| 30 | [(2,6-dimethylpiperidin-1-yl)carbamoyl]methyl benzoate i | -1 | View |
| 31 | [(4-hydroxypiperidin-1-yl)carbamoyl]methyl benzoate i | -1.23 | View |
| 32 | [(4-methylpiperazin-1-yl)carbamoyl]methyl benzoate hydrochloride i | -1.33 | View |
| 33 | {[4-(2-hydroxyethyl)piperazin-1-yl]carbamoyl}methyl benzoate hydrochloride i | -1.35 | View |
| 34 | 1-[2-(benzoyloxy)acetamido]azetidine-2-carboxylic acid i | -1.39 | View |
| 35 | 1-[2-(benzoyloxy)acetamido]pyrrolidine-2-carboxylic acid i | -1.29 | View |
| 36 | methyl 1-[2-(benzoyloxy)acetamido]pyrrolidine-2-carboxylate i | -1.21 | View |
| 37 | [(2-carbamoylpyrrolidin-1-yl)carbamoyl]methyl benzoate i | -1.41 | View |
Nielsenw, N. M.; Bundgaard, H. Glycolamide esters as biolabile prodrugs of carboxylic acid agents: Synthesis, stability, bioconversion, and physicochemical properties. Journal of Pharmaceutical Sciences 1988, 77, 285–298. http://dx.doi.org/10.1002/jps.2600770402