REPOSITORY ABOUT GUIDELINES CITING BLOG

10967/142 - QDB Compounds

QsarDB Repository

Franke, R.; Gruska, A.; Giuliani, A.; Benigni, R. Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model. Carcinogenesis 2001, 22, 1561–1571.

64 compounds | Property Potency: Carcinogenic potency as log(MW/TD50) [log((mol/kg)/TD50)]

ID Name Potency Details
1 2-Naphthylamine 31.812977 View
2 Benzidine 30.701297 View
3 2-Acetylaminofluorene 31.316399 View
4 Isopropyl-N-(3-chlorophenyl)carbamate 25.704177 View
5 4,4'-Methylenebis(2-chloroaniline) 30.374841 View
6 o-Toluidine i 30.312155 View
7 2-Biphenylamine hydrochloride i 32.495717 View
8 2,6-Dichloro-p-phenylenediamine 29.243666 View
9 4,4'-Methylenedianiline dihydrochloride i 31.141457 View
10 Monuron 29.438709 View
11 4,4'-Oxydianiline 30.013225 View
12 2,6-Xylidine 32.281568 View
13 o-Anthranilic acid 27.651058 View
14 Acetamide, N-​[4-​(2-​chloroacetyl)​phenyl]​- i 28.112443 View
15 2-Chloro-p-phenylenediamine sulphate i 27.574515 View
16 2,4-Dimethoxyaniline hydrochloride i 28.662278 View
17 4-Nitroanthranilic acid 28.565774 View
18 4-Nitro-o-phenylenediamine 27.846439 View
19 p-Phenylenediamine dihydrochloride i 28.353338 View
20 N-Phenyl-p-phenylenediamine 28.66891 View
21 1-Phenyl-2-thiourea 25.890942 View
22 1,​4-​Benzenediamine, 2-​methyl-​, sulfate i 28.312969 View
23 3-Amino-4-ethoxyacetanilide 32.078816 View
24 3-Amino-9-ethylcarbazole i 30.11006 View
25 4-Amino-2-nitrophenol 30.976417 View
26 Aniline hydrochloride i 30.584329 View
27 o-Anisidine i 29.845678 View
28 p-Chloroaniline hydrochloride i 29.141363 View
29 4-Chloro-m-phenylenediamine 29.732037 View
30 4-Chloro-o-phenylenediamine 28.307538 View
31 3-Chloro-p-toluidine 29.108589 View
32 m-Cresidine 29.533803 View
33 p-Cresidine 30.795875 View
34 Dapsone i 30.445915 View
35 2,4-Diaminoanisole sulfate i 29.752109 View
36 2,4-Diaminotoluene i 30.503514 View
37 1,5-Naphthalenediamine 30.291436 View
38 3-Nitro-p-acetophenetide 31.118461 View
39 Benzenamine, 2-​methoxy-​5-​nitro- i 29.683528 View
40 4,4'-Thiodianiline 29.663216 View
41 2,4,5-Trimethylaniline 30.690156 View
42 4-Aminobiphenyl 31.384286 View
43 2-Amino-5-nitrophenol 28.043143 View
44 2,4-Diaminophenol dihydrochloride i 29.285568 View
45 4-Acetylaminobiphenyl 31.48436 View
46 4'-Fluoro-4-aminodiphenyl 30.717083 View
47 4-Acetylamino-4'-fluorobiphenyl i 30.859044 View
48 N-(2-Fluorenyl)-2,2,2-trifluoroacetamide 31.720341 View
49 4-Chloro-4'-aminodiphenyl ether i 31.112002 View
50 3,3'-Dichlorobenzidine 29.702301 View
51 Acedapsone i 30.202766 View
52 Phenacetin 29.577049 View
53 o-Phenylenediamine dihydrochloride i 29.376852 View
54 3,3',4,4'-Tetraaminobiphenyl tetrahydrochloride i 30.11309 View
55 1,3-Benzenediamine, 2,4,5,6-tetrafluoro- i 28.637859 View
56 2,4,6-Trimethylanilinium chloride i 31.811782 View
57 p-Toluidine hydrochloride i 29.913306 View
58 2-Amino-4-nitrophenol 29.611704 View
59 2,4,6-Trichloroaniline 30.188203 View
60 m-Toluidine hydrochloride i 28.157319 View
61 3,3'-Dimethoxybenzidine dihydrochloride i 29.946611 View
62 o-Toluidine dihydrochloride i 30.278359 View
63 Chloramben 30.64138 View
64 4,4'-Methylenebis (2-methylaniline) 30.956058 View

Bibliography

  1. Franke, R.; Gruska, A.; Giuliani, A.; Benigni, R. Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model. Carcinogenesis 2001, 22, 1561–1571. http://dx.doi.org/10.1093/carcin/22.9.1561