Franke, R.; Gruska, A.; Giuliani, A.; Benigni, R. Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model. Carcinogenesis 2001, 22, 1561–1571.

Compound

	ID:	19
	Name:	p-Phenylenediamine dihydrochloride
	Description:	Changed name from the original p-Phenylenediamine · 2HCl to p-Phenylenediamine dihydrochloride. The authors most likely used the cation for the calculations.
	Labels:
	CAS:	624-18-0
	InChi Code:	InChI=1S/C6H8N2.2ClH/c7-5-1-2-6(8)4-3-5;;/h1-4H,7-8H2;2*1H

Properties

Carcinogenicity: Class: C - Carcinogenic, nC -non-Carcinogenic

Value	Source or prediction
nC	experimental value
nC	Eq.5: Carcinogenic class of aromatic amines (Training set.)

Potency: Carcinogenic potency as log(MW/TD50) [log((mol/kg)/TD50)]

Value	Source or prediction
28.353338	experimental value

Links to External Resources

Link	Resource description
DTXSID8021141	US EPA CompTox Dashboard