Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.
Compound
| ID: | 302 | |
|---|---|---|
| Name: | Zidovudine | |
| Description: | Alternative name from original table: (AZT) | |
| Labels: | Plasma, in_vivo | |
| CAS: | ||
| InChi Code: | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18) |
Properties
logBB: Blood-brain distribution
| Value | Source or prediction |
|---|---|
| -0.72 |
experimental value |
| -0.468 |
Eq2: Model for drug-like chemicals, in vivo (Training set) |
| -0.4483 |
Eq5: Model for all chemicals, in vivo and in vitro (Training set) |