Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.
Compound
| ID: | 194 | |
|---|---|---|
| Name: | Mefloquine | |
| Description: | Alternative name from original table: (+ve) (AI-8) | |
| Labels: | Plasma, in_vivo | |
| CAS: | ||
| InChi Code: | InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2 |
Properties
logBB: Blood-brain distribution
| Value | Source or prediction |
|---|---|
| 0.63 |
experimental value |
| 0.276 |
Eq2: Model for drug-like chemicals, in vivo (Training set) |
| 0.2917 |
Eq5: Model for all chemicals, in vivo and in vitro (Training set) |