Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.

Compound

	ID:	180
	Name:	Hydroxyzine
	Description:
	Labels:	Blood, in_vivo
	CAS:
	InChi Code:	InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2

Properties

logBB: Blood-brain distribution

Value	Source or prediction
0.39	experimental value
0.159	Eq2: Model for drug-like chemicals, in vivo (Training set)
0.1674	Eq5: Model for all chemicals, in vivo and in vitro (Training set)

Links to External Resources

Link	Resource description
DTXSID8023137	US EPA CompTox Dashboard