Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.

Compound

	ID:	151
	Name:	Codeine
	Description:
	Labels:	Plasma, in_vivo
	CAS:
	InChi Code:	InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3

Properties

logBB: Blood-brain distribution

Value	Source or prediction
-0.22	experimental value
-0.157	Eq2: Model for drug-like chemicals, in vivo (Training set)
-0.1488	Eq5: Model for all chemicals, in vivo and in vitro (Training set)