Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.

Compound

	ID:	105
	Name:	4-Hydroxymidazolam
	Description:
	Labels:	Serum, in_vivo
	CAS:
	InChi Code:	InChI=1S/C18H13ClFN3O/c1-10-21-9-16-18(24)22-17(12-4-2-3-5-14(12)20)13-8-11(19)6-7-15(13)23(10)16/h2-9,18,24H,1H3

Properties

logBB: Blood-brain distribution

Value	Source or prediction
-0.03	experimental value
0.235	Eq2: Model for drug-like chemicals, in vivo (Training set)
0.1995	Eq5: Model for all chemicals, in vivo and in vitro (Training set)