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Browsing QMRFs for mutagenicity models by Endpoint "4. Human health effects 4.10. Mutagenicity"

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Browsing QMRFs for mutagenicity models by Endpoint "4. Human health effects 4.10. Mutagenicity"

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  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_100 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), because ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_102+wp2 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_1535 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_97+1537 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_98 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), because ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m100 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m102+wp2 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m1535 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m97+1537 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m98 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), because ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_NIHS The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_Risk Abstract The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient ...