Published: Mare Oja, Sulev Sild, Uko Maran (2019-02-21)
Abstract: Permeability is used to describe and evaluate the absorption of drug substances in the human gastrointestinal tract (GIT). Permeability is largely dependent on fluctuating pH that causes the ionization of drug substances and also influences regional absorption in the GIT. Therefore, classification models that characterize permeability at wide range of pH-s ...
Toxicokinetics Classification DescriptorCalculation