27 compounds | Property pIC50: Antiproliferative activity [cm/s]
| ID | Name | pIC50 | Details |
|---|---|---|---|
| 1 | 9-(5-bromo-2-hydroxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.28 | View |
| 2 | 2,6,7-trihydroxy-9-(2-hydroxy-3-methoxyphenyl)-3H-xanthen-3-one | 5.05 | View |
| 3 | 9-(3,4-dihydroxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 4.56 | View |
| 4 | 9-(3,4-dimethoxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.31 | View |
| 6 | 2,6,7-trihydroxy-9-(4-hydroxy-3-methoxy-5-nitrophenyl)-3H-xanthen-3-one | 4.44 | View |
| 7 | 9-(4-ethoxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.54 | View |
| 8 | 9-[4-(dimethylamino)phenyl]-2,6,7-trihydroxy-3H-xanthen-3-one | 5.3 | View |
| 9 | 2,6,7-trihydroxy-9-[4-(trifluoromethyl)phenyl]-3H-xanthen-3-one | 6.15 | View |
| 10 | N-[4-(2,6,7-trihydroxy-3-oxo-3H-xanthen-9-yl)phenyl]acetamide | 4.39 | View |
| 11 | 9-(3-bromophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.82 | View |
| 13 | 9-(2-chlorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 4.76 | View |
| 14 | 9-(4-chlorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.55 | View |
| 15 | 9-(4-fluorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.17 | View |
| 17 | 9-(3-chlorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.14 | View |
| 18 | 2,6,7-trihydroxy-9-(2-hydroxy-5-nitrophenyl)-3H-xanthen-3-one | 4.04 | View |
| 20 | 2,6,7-trihydroxy-9-(4-nitrophenyl)-3H-xanthen-3-one | 4.38 | View |
| 24 | 9-(2-hydroxy-3-methoxyphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.01 | View |
| 34 | 9-(2-bromo-4-methylphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 5.25 | View |
| 36 | 9-(3,5-dibromophenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.2 | View |
| 38 | 9-(5-bromo-2-hydroxyphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.21 | View |
| 42 | 3,3,6,6-tetramethyl-9-(2,4,6-trimethoxyphenyl)-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.6 | View |
| 44 | 9-(2,5-dimethoxyphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.57 | View |
| 12 | 9-(2-chloro-6-fluorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 5.34 | View |
| 16 | 2,6,7-trihydroxy-9-(2-methoxyphenyl)-3H-xanthen-3-one | 4.44 | View |
| 19 | 2,6,7-trihydroxy-9-phenyl-3H-xanthen-3-one | 5.23 | View |
| 23 | 9-(3,4-dihydroxyphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.06 | View |
| 40 | 9-(5-bromo-2,3-dimethoxyphenyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione | 4.61 | View |
Zukić, S.; Maran, U. Modelling of antiproliferative activity measured in HeLa cervical cancer cells in a series of xanthene derivatives. SAR and QSAR in Environmental Research 2020, 31, 905–921. https://doi.org/10.1080/1062936x.2020.1839131