Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.
Compound
| ID: | 9 | |
|---|---|---|
| Name: | Dapson | |
| Description: | ||
| Labels: | pH7.4, Base | |
| CAS: | 80-08-0 | |
| InChi Code: | InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2 |
Properties
logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i
| Value | Source or prediction |
|---|---|
| -7.06 |
experimental value |
| -6.58 |
Eq4: QSAR model for permeability of drugs and drug-like compounds (Training set) |