Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.
Compound
| ID: | 71 | |
|---|---|---|
| Name: | Sulindac | |
| Description: | ||
| Labels: | pH3, Acid | |
| CAS: | 38194-50-2 | |
| InChi Code: | InChI=1S/C20H19FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10,13,15H,11H2,1-2H3,(H,22,23)/b17-9+ |
Properties
logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i
| Value | Source or prediction |
|---|---|
| -5.48 |
experimental value |
| -5.49 |
Eq4: QSAR model for permeability of drugs and drug-like compounds (External validation set) |