Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.

Compound

	ID:	60
	Name:	Azelastine
	Description:
	Labels:	pH9, Base
	CAS:	58581-89-8
	InChi Code:	InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3/t18-/m0/s1

Properties

logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i

Value	Source or prediction
-4.25	experimental value
-4.07	Eq4: QSAR model for permeability of drugs and drug-like compounds (External validation set)

Links to External Resources

Link	Resource description
DTXSID6022638	US EPA CompTox Dashboard