Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.
Compound
| ID: | 59 | |
|---|---|---|
| Name: | Amoxapine | |
| Description: | ||
| Labels: | pH9, Base | |
| CAS: | 14028-44-5 | |
| InChi Code: | InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 |
Properties
logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i
| Value | Source or prediction |
|---|---|
| -4.18 |
experimental value |
| -5.18 |
Eq4: QSAR model for permeability of drugs and drug-like compounds (External validation set) |
Links to External Resources
| Link | Resource description |
|---|---|
| DTXSID7022598 | US EPA CompTox Dashboard |