Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.
Compound
| ID: | 51 | |
|---|---|---|
| Name: | Orbifloxacin | |
| Description: | ||
| Labels: | pH7.4, Ampholyte | |
| CAS: | 113617-63-3 | |
| InChi Code: | InChI=1S/C19H20F3N3O3/c1-8-5-24(6-9(2)23-8)17-14(21)13(20)12-16(15(17)22)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6H2,1-2H3,(H,27,28)/t8-,9+ |
Properties
logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i
| Value | Source or prediction |
|---|---|
| -7.42 |
experimental value |
| -6.74 |
Eq4: QSAR model for permeability of drugs and drug-like compounds (Validation set) |
Links to External Resources
| Link | Resource description |
|---|---|
| DTXSID7046201 | US EPA CompTox Dashboard |