Oja, M.; Maran, U. The permeability of artificial membrane for the wide range of pH in human gastrointestinal tract: experimental measurements and quantitative structure-activity relationship. Mol. Inf. 2015, 34, 493–506.
Compound
| ID: | 11 | |
|---|---|---|
| Name: | Dexamethasone | |
| Description: | ||
| Labels: | pH9, Neutral | |
| CAS: | 50-02-2 | |
| InChi Code: | InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 |
Properties
logPeff: Highest logarithmic effective membrane permeability for pH range 3 to 9 [log(cm/s)] i
| Value | Source or prediction |
|---|---|
| -7.12 |
experimental value |
| -6.39 |
Eq4: QSAR model for permeability of drugs and drug-like compounds (Training set) |
Links to External Resources
| Link | Resource description |
|---|---|
| DTXSID3020384 | US EPA CompTox Dashboard |