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Browsing by Species "Salmonella typhimurium and Escherichia coli"

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Browsing by Species "Salmonella typhimurium and Escherichia coli"

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  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_NIHS The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_Risk Abstract The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient ...