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Browsing by Species "Salmonella typhimurium (strain TA98)"

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Browsing by Species "Salmonella typhimurium (strain TA98)"

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  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_98 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), because ...
  • HumanHealth Classification QMRF
    Published: Michael Lawless (2021-09-02)
    Abstract: MUT_m98 The Ames bacterial mutagenicity test is an important regulatory screen for potential carcinogenicity. In silico prediction of Ames positivity plays two important but somewhat distinct roles in the discovery and development of biologically active compounds. A positive Ames test does not necessarily derail development of an active ingredient (AI), because ...