REPOSITORY QDB RESOURCES CITING NEWS CONTACTS

10967/60 - QDB Compounds

QsarDB Repository

Schultz, T.W.; Yarbrough, J.W.; Koss, S.K. Identification of reactive toxicants: Structure-activity relationships for amides. Cell Biol. Toxicol. 2006, 22, 5, 339–349.

29 compounds | Property pIGC50: 40-h Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

ID Name pIGC50 Details
1 Acetamide -2.32 View
2 Propionamide -2.09 View
3 n-Butyramide -1.79 View
4 2-Methylpropionamide -1.85 View
5 Trimethylacetamide -1.48 View
6 n-Hexanoamide -0.91 View
7 N-Methylpropionamide -1.53 View
8 N-Ethylacetamide -1.70 View
9 N-Propylacetamide -1.50 View
10 N-(tert)Butylacetamide -1.16 View
11 N,N-Dimethylacetamide -1.95 View
12 N,N-Diethylacetamide -1.54 View
13 N,N-Dimethylpropionamide -1.50 View
14 2-Fluoroacetamide NTAS View
15 2-Chloroacetamide 0.03 View
16 2,2-Dichloroacetamide -0.98 View
17 2,2,2-Trichloroacetamide -0.29 View
18 2-Bromoacetamide 1.52 View
19 2-Chloropropionamide -1.44 View
20 2-Bromopropionamide 0.00 View
21 3-Chloropriopionamide -1.59 View
22 2,3-Dibromopropionamide 1.91 View
23 2-Chlorobutyramide -1.22 View
24 2-Chloro-N,N-diethylacetamide 0.52 View
25 Acrylamide -0.81 View
26 N-Isopropylacrylamide -1.31 View
27 N-phenylacrylamide 0.12 View
28 N,N-Dimethylacrylamide -1.24 View
29 N,N'-Methylenebisacrylamide -0.51 View

Bibliography

  1. Schultz, T. W.; Yarbrough, J. W.; Koss, S. K. Identification of reactive toxicants: Structure-activity relationships for amides. Cell Biol. Toxicol. 2006, 22, 339–349. http://dx.doi.org/10.1007/s10565-006-0079-z

  2. Schultz, T. W. TETRATOX: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. Toxicol. Mech. Meth. 1997, 7, 289–309. http://dx.doi.org/10.1080/105172397243079