10967/259 - QDB Compounds

QsarDB Repository

Piir, G.; Sild, S.; Maran, U. Interpretable machine learning for the identification of estrogen receptor agonists, antagonists, and binders. Chemosphere 2023.

Compound

ID:t199
Name:3-Buten-2-one, 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-
Description:
Labels:
CAS:127-51-5
InChi Code:InChI=1S/C14H22O/c1-10-7-6-8-14(4,5)13(10)9-11(2)12(3)15/h7,9,13H,6,8H2,1-5H3/b11-9+

Properties

er_ago: Activity in ER agonist pathway

ValueSource or prediction
agonist

experimental value

agonist

Tab3.agonists: Model for ER activity on agonists pathway (Training set)

inactive

Tab3.agonists: Model for ER activity on agonists pathway (Out of bag)

er_ant: Activity in ER antagonist pathway

ValueSource or prediction
inactive

experimental value

inactive

Tab3.antagonists: Model for ER activity on antagonists pathway (Test set)

er_bin: Binding activity in estrogen receptor

ValueSource or prediction
binder

experimental value

binder

Tab3.binders: Model for binding in ER (Training set)

inactive

Tab3.binders: Model for binding in ER (Out of bag)