Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.
Compound
| ID: | 277 | |
|---|---|---|
| Name: | Stavudine | |
| Description: | ||
| Labels: | Plasma, in_vivo | |
| CAS: | ||
| InChi Code: | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15) |
Properties
logBB: Blood-brain distribution
| Value | Source or prediction |
|---|---|
| -0.48 |
experimental value |
| -0.823 |
Eq2: Model for drug-like chemicals, in vivo (Training set) |
| -0.7874 |
Eq5: Model for all chemicals, in vivo and in vitro (Training set) |