@ARTICLE{El-Adl2022-zg-11,
  title     = "Design, synthesis, docking, and anticancer evaluations of
               phthalazines as {VEGFR-2} inhibitors",
  author    = "El-Adl, Khaled and Ibrahim, Mohamed K and Khedr, Fathalla and
               Abulkhair, Hamada S and Eissa, Ibrahim H",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  355,
  number    =  1,
  pages     = "e2100278",
  month     =  jan,
  year      =  2022,
  doi       = "10.1002/ardp.202100278",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{Khedr2021-zi-12,
  title     = "Phthalazine-based {VEGFR-2} inhibitors: Rationale, design,
               synthesis, in silico, {ADMET} profile, docking, and anticancer
               evaluations",
  author    = "Khedr, Fathalla and Ibrahim, Mohamed-Kamal and Eissa, Ibrahim H
               and Abulkhair, Hamada S and El-Adl, Khaled",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  354,
  number    =  11,
  pages     = "e2100201",
  month     =  nov,
  year      =  2021,
  doi       = "10.1002/ardp.202100201",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{El-Adl2021-xs-13,
  title     = "{N-Substituted-4-phenylphthalazin-1-amine-derived} {VEGFR-2}
               inhibitors: Design, synthesis, molecular docking, and anticancer
               evaluation studies",
  author    = "El-Adl, Khaled and Ibrahim, Mohamed-Kamal and Khedr, Fathalla
               and Abulkhair, Hamada S and Eissa, Ibrahim H",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  354,
  number    =  3,
  pages     = "e2000219",
  month     =  mar,
  year      =  2021,
  doi       = "10.1002/ardp.202000219",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{El-Helby2017-wk-14,
  title     = "Design, synthesis, molecular docking, and anticancer activity of
               phthalazine derivatives as {VEGFR-2} inhibitors",
  author    = "El-Helby, Abdel-Ghany A and Ayyad, Rezk R A and Sakr, Helmy and
               El-Adl, Khaled and Ali, Mamdouh M and Khedr, Fathalla",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  350,
  number    =  12,
  pages     = "1700240",
  month     =  dec,
  year      =  2017,
  doi       = "10.1002/ardp.201700240",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{AbdelHaleem2020-sg-15,
  title     = "Selective {VEGFR-2} inhibitors: Synthesis of pyridine
               derivatives, cytotoxicity and apoptosis induction profiling",
  author    = "AbdelHaleem, Amal and Mansour, Amira O and AbdelKader, Marwa and
               Arafa, Reem K",
  journal   = "Bioorg. Chem.",
  publisher = "Elsevier BV",
  volume    =  103,
  number    =  104222,
  pages     = "104222",
  month     =  oct,
  year      =  2020,
  doi       = "10.1016/j.bioorg.2020.104222",
  language  = "en"
}

@ARTICLE{Saleh2021-ef-16,
  title     = "Pyridine-derived {VEGFR-2} inhibitors: Rational design,
               synthesis, anticancer evaluations, in silico {ADMET} profile,
               and molecular docking",
  author    = "Saleh, Nashwa M and Abdel-Rahman, Adel A-H and Omar, Asmaa M and
               Khalifa, Mohamed M and El-Adl, Khaled",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  354,
  number    =  8,
  pages     = "e2100085",
  month     =  aug,
  year      =  2021,
  doi       = "10.1002/ardp.202100085",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{Elkaeed2022-hb-17,
  title     = "Discovery of new {VEGFR-2} inhibitors: Design, synthesis,
               anti-proliferative evaluation, docking, and {MD} simulation
               studies",
  author    = "Elkaeed, Eslam B and Yousef, Reda G and Khalifa, Mohamed M and
               Ibrahim, Albaraa and Mehany, Ahmed B M and Gobaara, Ibraheem M M
               and Alsfouk, Bshra A and Eldehna, Wagdy M and Metwaly, Ahmed M
               and Eissa, Ibrahim H and El-Zahabi, Mohamed Ayman",
  journal   = "Molecules",
  publisher = "MDPI AG",
  volume    =  27,
  number    =  19,
  pages     = "6203",
  month     =  sep,
  year      =  2022,
  doi       = "10.3390/molecules27196203",
  copyright = "https://creativecommons.org/licenses/by/4.0/",
  language  = "en"
}

@ARTICLE{Yousef2022-vf-18,
  title     = "Discovery of new nicotinamides as apoptotic {VEGFR-2}
               inhibitors: virtual screening, synthesis, anti-proliferative,
               immunomodulatory, {ADMET}, toxicity, and molecular dynamic
               simulation studies",
  author    = "Yousef, Reda G and Ibrahim, Albaraa and Khalifa, Mohamed M and
               Eldehna, Wagdy M and Gobaara, Ibraheem M M and Mehany, Ahmed B M
               and Elkaeed, Eslam B and Alsfouk, Aisha A and Metwaly, Ahmed M
               and Eissa, Ibrahim H",
  journal   = "J. Enzyme Inhib. Med. Chem.",
  publisher = "Informa UK Limited",
  volume    =  37,
  number    =  1,
  pages     = "1389--1403",
  month     =  dec,
  year      =  2022,
  doi       = "10.1080/14756366.2022.2070744",
  copyright = "http://creativecommons.org/licenses/by/4.0/",
  language  = "en"
}

@ARTICLE{El-Adl2020-ck-19,
  title     = "Design, synthesis, molecular docking, and anticancer evaluations
               of {1-benzylquinazoline-2,4(1H,3H)-dione} bearing different
               moieties as {VEGFR-2} inhibitors",
  author    = "El-Adl, Khaled and El-Helby, Abdel-Ghany A and Sakr, Helmy and
               El-Hddad, Sanadelaslam S A",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  353,
  number    =  8,
  pages     = "e2000068",
  month     =  aug,
  year      =  2020,
  doi       = "10.1002/ardp.202000068",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{Abdallah2021-qm-20,
  title     = "Design, synthesis and molecular modeling of new
               quinazolin-4(3H)-one based {VEGFR-2} kinase inhibitors for
               potential anticancer evaluation",
  author    = "Abdallah, Abdallah E and Eissa, Sally I and Al Ward, Maged
               Mohammed Saleh and Mabrouk, Reda R and Mehany, Ahmed B M and
               El-Zahabi, Mohamed Ayman",
  journal   = "Bioorg. Chem.",
  publisher = "Elsevier BV",
  volume    =  109,
  number    =  104695,
  pages     = "104695",
  month     =  apr,
  year      =  2021,
  doi       = "10.1016/j.bioorg.2021.104695",
  language  = "en"
}

@ARTICLE{El-Helby2019-na-21,
  title     = "Design, synthesis, molecular docking, and anticancer activity of
               benzoxazole derivatives as {VEGFR-2} inhibitors",
  author    = "El-Helby, Abdel-Ghany A and Sakr, Helmy and Eissa, Ibrahim H and
               Abulkhair, Hamada and Al-Karmalawy, Ahmed A and El-Adl, Khaled",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  352,
  number    =  10,
  pages     = "e1900113",
  month     =  oct,
  year      =  2019,
  doi       = "10.1002/ardp.201900113",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{El-Helby2019-zp-22,
  title     = "Benzoxazole/benzothiazole-derived {VEGFR-2} inhibitors: Design,
               synthesis, molecular docking, and anticancer evaluations",
  author    = "El-Helby, Abdel-Ghany A and Sakr, Helmy and Eissa, Ibrahim H and
               Al-Karmalawy, Ahmed A and El-Adl, Khaled",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  352,
  number    =  12,
  pages     = "e1900178",
  month     =  dec,
  year      =  2019,
  doi       = "10.1002/ardp.201900178",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{Ahmed2020-bm-23,
  title     = "{VEGFR-2} inhibiting effect and molecular modeling of newly
               synthesized coumarin derivatives as anti-breast cancer agents",
  author    = "Ahmed, Eman Y and Abdel Latif, Nehad A and El-Mansy, Mohamed F
               and Elserwy, Weam S and Abdelhafez, Omaima M",
  journal   = "Bioorg. Med. Chem.",
  publisher = "Elsevier BV",
  volume    =  28,
  number    =  5,
  pages     = "115328",
  month     =  mar,
  year      =  2020,
  doi       = "10.1016/j.bmc.2020.115328",
  language  = "en"
}

@ARTICLE{El-Adl2022-bp-24,
  title     = "New quinoxalin-2(1H)-one-derived {VEGFR-2} inhibitors: Design,
               synthesis, in vitro anticancer evaluations, in silico {ADMET},
               and docking studies",
  author    = "El-Adl, Khaled and Sakr, Helmy M and Yousef, Reda G and Mehany,
               Ahmed B M and Abulkhair, Hamada S and Eissa, Ibrahim H",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  355,
  number    =  7,
  pages     = "e2200048",
  month     =  jul,
  year      =  2022,
  doi       = "/10.1002/ardp.202200048",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{Alanazi2021-ot-25,
  title     = "Design, synthesis, docking, {ADMET} studies, and anticancer
               evaluation of new 3-methylquinoxaline derivatives as {VEGFR-2}
               inhibitors and apoptosis inducers",
  author    = "Alanazi, Mohammed M and Eissa, Ibrahim H and Alsaif, Nawaf A and
               Obaidullah, Ahmad J and Alanazi, Wael A and Alasmari, Abdullah F
               and Albassam, Hussam and Elkady, Hazem and Elwan, Alaa",
  journal   = "J. Enzyme Inhib. Med. Chem.",
  publisher = "Informa UK Limited",
  volume    =  36,
  number    =  1,
  pages     = "1760--1782",
  month     =  dec,
  year      =  2021,
  doi       = "10.1080/14756366.2021.1956488",
  copyright = "http://creativecommons.org/licenses/by/4.0/",
  language  = "en"
}

@ARTICLE{Abdelgawad2022-ez-26,
  title     = "Design, molecular docking, synthesis, anticancer and
               anti-hyperglycemic assessments of thiazolidine-2,4-diones 
               bearing sulfonylthiourea moieties as potent {VEGFR-2} inhibitors
               and {PPARy} agonists",
  author    = "Abdelgawad, Mohamed A and El-Adl, Khaled and El-Hddad,
               Sanadelaslam S A and Elhady, Mostafa M and Saleh, Nashwa M and
               Khalifa, Mohamed M and Khedr, Fathalla and Alswah, Mohamed and
               Nayl, Abdelaziz A and Ghoneim, Mohammed M and Abd El-Sattar,
               Nour E A",
  journal   = "Pharmaceuticals (Basel)",
  publisher = "MDPI AG",
  volume    =  15,
  number    =  2,
  pages     = "226",
  month     =  feb,
  year      =  2022,
  doi       = "10.3390/ph15020226",
  copyright = "https://creativecommons.org/licenses/by/4.0/",
  language  = "en"
}

@ARTICLE{El-Adl2021-ep-27,
  title     = "Design, synthesis, docking, {ADMET} profile, and anticancer
               evaluations of novel thiazolidine-2,4-dione derivatives as
               {VEGFR-2} inhibitors",
  author    = "El-Adl, Khaled and Sakr, Helmy and El-Hddad, Sanadelaslam S A
               and El-Helby, Abdel-Ghany A and Nasser, Mohamed and Abulkhair,
               Hamada S",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  354,
  number    =  7,
  pages     = "e2000491",
  month     =  jul,
  year      =  2021,
  doi       = "10.1002/ardp.202000491",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{El-Adl2021-ed-28,
  title     = "Design, synthesis, molecular docking, anticancer evaluations,
               and in silico pharmacokinetic studies of novel
               5-[(4-chloro/2,4-dichloro)benzylidene]thiazolidine-2,4-dione
               derivatives as {VEGFR-2} inhibitors",
  author    = "El-Adl, Khaled and El-Helby, Abdel-Ghany A and Sakr, Helmy and
               Ayyad, Rezk R and Mahdy, Hazem A and Nasser, Mohamed and
               Abulkhair, Hamada S and El-Hddad, Sanadelaslam S A",
  journal   = "Arch. Pharm. (Weinheim)",
  publisher = "Wiley",
  volume    =  354,
  number    =  2,
  pages     = "e2000279",
  month     =  feb,
  year      =  2021,
  doi       = "10.1002/ardp.202000279",
  copyright = "http://onlinelibrary.wiley.com/termsAndConditions\#vor",
  language  = "en"
}

@ARTICLE{El-Adl2020-os-29,
  title     = "Design, synthesis, molecular docking and anticancer evaluations
               of 5-benzylidenethiazolidine-2,4-dione derivatives targeting
               {VEGFR-2} enzyme",
  author    = "El-Adl, Khaled and El-Helby, Abdel-Ghany A and Sakr, Helmy and
               Eissa, Ibrahim H and El-Hddad, Sanadelaslam S A and M I A
               Shoman, Fatma",
  journal   = "Bioorg. Chem.",
  publisher = "Elsevier BV",
  volume    =  102,
  number    =  104059,
  pages     = "104059",
  month     =  sep,
  year      =  2020,
  doi       = "j.bioorg.2020.104059",
  language  = "en"
}

@ARTICLE{Elkaeed2022-lp-30,
  title     = "New quinoline and isatin derivatives as apoptotic {VEGFR-2}
               inhibitors: design, synthesis, anti-proliferative activity,
               docking, {ADMET}, toxicity, and {MD} simulation studies",
  author    = "Elkaeed, Eslam B and Taghour, Mohammed S and Mahdy, Hazem A and
               Eldehna, Wagdy M and El-Deeb, Nehal M and Kenawy, Ahmed M and A
               Alsfouk, Bshra and Dahab, Mohammed A and Metwaly, Ahmed M and
               Eissa, Ibrahim H and El-Zahabi, Mohamed A",
  journal   = "J. Enzyme Inhib. Med. Chem.",
  publisher = "Informa UK Limited",
  volume    =  37,
  number    =  1,
  pages     = "2191--2205",
  month     =  dec,
  year      =  2022,
  doi       = "10.1080/14756366.2022.2110869",
  copyright = "http://creativecommons.org/licenses/by/4.0/",
  language  = "en"
}
