Schultz, T.W.; Arnold, L.M.; Wilke, T.S.; Moulton, M.P. Relationships of quantitative structure-activity for normal aliphatic alcohols. Ecotoxicol. Environ. Saf. 1990, 19, 3, 243–253.

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Schultz, T.W.; Arnold, L.M.; Wilke, T.S.; Moulton, M.P. Relationships of quantitative structure-activity for normal aliphatic alcohols. Ecotoxicol. Environ. Saf. 1990, 19, 3, 243–253.

QDB archive DOI: 10.15152/QDB.26   DOWNLOAD

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Property logIGC50: 48-h Tetrahymena toxicity as log(IGC50) [log(mol/L)]

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When using this QDB archive, please cite (see details) it together with the original article:

  • Ruusmann, V. Data for: Relationships of quantitative structure-activity for normal aliphatic alcohols. QsarDB repository, QDB.26. 2012. http://dx.doi.org/10.15152/QDB.26

  • Schultz, T. W.; Arnold, L. M.; Wilke, T. S.; Moulton, M. P. Relationships of quantitative structure-activity for normal aliphatic alcohols. Ecotoxicol. Environ. Saf. 1990, 19, 243–253. http://dx.doi.org/10.1016/0147-6513(90)90026-2

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dc.date.accessioned2012-05-23T15:40:40Z
dc.date.available2012-05-23T15:40:40Z
dc.date.issued2012-05-23
dc.identifier.urihttp://hdl.handle.net/10967/26
dc.identifier.urihttp://dx.doi.org/10.15152/QDB.26
dc.description.abstractThe relative toxicity of 14 normal aliphatic alcohols has been determined as 48-hr 50% population growth inhibition (log BR, biological response) of Tetrahymena pyriformis. A linear relationship was observed between log BR and the 1-octanol/water partition coefficient (log Kow). Comparison of log BR with 96-hr 50% mortality data for Pimephales promelas revealed excellent agreement between the two test systems. A relatively constant steady-state biophase toxicant concentration is calculated for each alcohol. Calculated chemical activity increased with an increase in hydrocarbon chain length. In addition, there was good agreement between chemical activity and the activity coefficient for narcosis.
dc.publisherVillu Ruusmann
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleSchultz, T.W.; Arnold, L.M.; Wilke, T.S.; Moulton, M.P. Relationships of quantitative structure-activity for normal aliphatic alcohols. Ecotoxicol. Environ. Saf. 1990, 19, 3, 243–253.
qdb.property.endpoint6. Other (Acute toxicity to ciliate protozoa)
qdb.property.speciesTetrahymena pyriformis
bibtex.entryarticle
bibtex.entry.authorSchultz, T. W.
bibtex.entry.authorArnold, L. M.
bibtex.entry.authorWilke, T. S.
bibtex.entry.authorMoulton, M. P.
bibtex.entry.doi10.1016/0147-6513(90)90026-2
bibtex.entry.journalEcotoxicol. Environ. Saf.
bibtex.entry.number3
bibtex.entry.pages243–253
bibtex.entry.titleRelationships of quantitative structure-activity for normal aliphatic alcohols
bibtex.entry.volume19
bibtex.entry.year1990


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