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Mombelli, E.; Pery, A. R. R. A Linear Model to Predict Chronic Effects of Chemicals on Daphnia magna. Bull. Environ. Contam. Toxicol. 2011, 87, 494–498.

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Mombelli, E.; Pery, A. R. R. A Linear Model to Predict Chronic Effects of Chemicals on Daphnia magna. Bull. Environ. Contam. Toxicol. 2011, 87, 494–498.

QDB archive DOI: 10.15152/QDB.167   DOWNLOAD

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Property pEC50_chronic: 21-day chronic Daphnia toxicity as log(1/EC50) [log(L/mmol)] i

Compounds: 244 | Models: 1 | Predictions: 2

Tab1: QAAR with acute toxicity to Daphnia i

Regression model (regression)

Open in:QDB Explorer QDB Predictor

Name Type n

R2

σ

Training set training 151 0.893 0.332
Validation set external validation 62 0.823 0.415

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dc.date.accessioned 2015-09-02T13:38:54Z
dc.date.available 2015-09-02T13:38:54Z
dc.date.issued 2015-09-02
dc.identifier.uri http://hdl.handle.net/10967/167
dc.identifier.uri http://dx.doi.org/10.15152/QDB.167
dc.description.abstract Chronic toxicity data for Daphnia magna are information requirements in the context of regulations on chemical safety. This paper proposes a linear model for the prediction of chemically-induced effects on the reproductive output of D. magna. This model is based on data retrieved from the Japanese Ministry of Environment database and it predicts chronic effects as a function of acute toxicity data. The proposed model proved to be able to predict chronic toxicities for chemicals not used in the training set. Our results suggest that experiments involving chronic exposure to chemicals could be reduced thanks to the proposed model.
dc.publisher Iiris Kahn
dc.rights Attribution 4.0 International
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.title Mombelli, E.; Pery, A. R. R. A Linear Model to Predict Chronic Effects of Chemicals on Daphnia magna. Bull. Environ. Contam. Toxicol. 2011, 87, 494–498.
qdb.property.endpoint 3. Ecotoxic effects 3.4. Long-term toxicity to Daphnia en_US
qdb.property.species Daphnia magna en_US
qdb.prediction.application R 2.12.0 en_US
bibtex.entry article en_US
bibtex.entry.author Mombelli, E.
bibtex.entry.author Pery, A. R. R.
bibtex.entry.doi 10.1007/s00128-011-0393-x en_US
bibtex.entry.journal Bull. Environ. Contam. Toxicol. en_US
bibtex.entry.month Sep
bibtex.entry.number 5 en_US
bibtex.entry.pages 494–498 en_US
bibtex.entry.title A Linear Model to Predict Chronic Effects of Chemicals on Daphnia magna en_US
bibtex.entry.volume 87 en_US
bibtex.entry.year 2011
qdb.model.type Regression model (regression) en_US


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