University of Tartu, Institute of Chemistry, Molecular Technology (Estonia)
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Browsing Miscellaneous publications (by other authors) by Title "A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data"

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Browsing Miscellaneous publications (by other authors) by Title "A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data"

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Abraham, M. H.; Ibrahim, A.; Zhao, Y.; Acree, W. E. A data base for partition of volatile organic compounds and drugs from blood/plasma/serum to brain, and an LFER analysis of the data. J. Pharm. Sci. 2006, 95, 10, 2091–2100.

Published: Iiris Kahn (2015-01-14)

Abstract: Literature values of the in vivo distribution (BB) of drugs from blood, plasma, or serum to rat brain have been assembled for 207 compounds (233 data points). Wefind that data on in vivo distribution from blood, plasma, and serum to rat brain can all be combined. Application of our general linear free energy relationship (LFER) to the 207 compounds yields an ...

Toxicokinetics Regression

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