Dearden, J.C.; Cronin, M.T.D.; Schultz, T.W.; Lin, D.T. QSAR Study of the Toxicity of Nitrobenzenes to Tetrahymena pyriformis. QSAR Comb. Sci. 1995, 14, 5, 427–432.

47 compounds | Property pIGC50: 48-h Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

ID	Name	pIGC50	Details
1	H	0.350	View
2	2-NH2	0.077	View
3	2-OH	0.770	View
4	2-CH3	0.479	View
5	2-Cl	0.676	View
6	2-Br	0.863	View
7	2-CN	1.076	View
8	2-CH2OH	-0.155	View
9	2-COOH	-1.637	View
10	2-C6H5	1.301	View
11	2-CONH2	-0.721	View
12	2-CHO	0.174	View
13	2-NO2	1.252	View
14	3-NH2	0.026	View
15	3-OH	0.506	View
16	3-CH3	0.572	View
17	3-Cl	0.836	View
18	3-Br	1.215	View
19	3-CN	0.451	View
20	3-CH2OH	-0.220	View
21	3-COOH	-1.089	View
22	3-C6H5	1.569	View
23	3-CONH2	-0.193	View
24	3-CHO	0.140	View
25	3-NO2	0.762	View
26	3-OCH3	0.670	View
27	3-COCH3	0.317	View
28	4-CH3	0.796	View
29	4-C2H5	0.804	View
30	4-OCH3	0.544	View
31	4-OC2H5	0.829	View
32	4-OC4H9	1.420	View
33	4-F	0.253	View
34	4-Cl	0.559	View
35	4-Br	0.461	View
36	4-CN	0.569	View
37	4-CH2CN	0.132	View
38	4-CH2Cl	1.180	View
39	4-CH=NOH	0.678	View
40	4-NHC6H5	1.886	View
41	4-CH2OH	0.101	View
42	4-COOH	-0.862	View
43	4-COOCH3	0.398	View
44	4-COOC2H5	0.710	View
45	4-CONH2	0.179	View
46	4-CHO	0.203	View
47	4-NO2	1.301	View

Bibliography

Dearden, J. C.; Cronin, M. T. D.; Schultz, T. W.; Lin, D. T. QSAR Study of the Toxicity of Nitrobenzenes to Tetrahymena pyriformis. QSAR Comb. Sci. 1995, 14, 427–432. http://dx.doi.org/10.1002/qsar.19950140503
Schultz, T. W.; Lin, D. T.; Wilke, T. S.; Arnold, L. M. Quantitative structure-activity relationships for the Tetrahymena pyriformis population growth endpoint: a mechanism of action approach. In Practical Applications of Quantitative Structure-Activity Relationships (QSAR) in Environmental Chemistry and Toxicology; Karcher, W.; Devillers, J., Eds.; Joint Research Centre; 1990.