10967/42 - QDB Compounds

QsarDB Repository

Sinks, G.D.; Schultz, T.W. Correlation of Tetrahymena and Pimephales Toxicity: Evaluation of 100 Additional Compounds. Environ. Toxicol. Chem. 2001, 20, 4, 917–921.

100 compounds | Property pIGC50: 2-day Tetrahymena toxicity as log(1/IGC50) [log(L/mmol)]

IDNamepIGC50Details
12-methyl-2,4-pentanediol-1.96View
2Trimethylphosphate-1.82View
31,4-Dicyanobutane-1.54View
4n,n-Diethylethanolamine-1.50View
5n,n-Diethylacetamide-1.54View
63-Methyl-1-pentyn-3-ol-1.32View
72,4-Diaminotoulene-0.66View
81-Benzylpyridinium-3-sulfonate-1.50View
9Cyclohexanone-1.23View
101,6-Dicyanohexane-0.77View
112-Ethylpyridine-0.87View
122-Methylimidazole-0.91View
13(+/-)-1,2-Dimethylpropylamine-0.71View
143'-Aminoacetophenone-0.82View
15Trans-3-hexen-1-ol-0.78View
16Cyclohexanone oxime-0.80View
17Diethyl benzylphosphonate-0.43View
182,4-Dimethyl-3-pentanol-0.71View
195-Methyl-2-hexanone-0.65View
203-(3-Pyridyl)-1-propanol-0.84View
213-Cyano-4,6-dimethyl-2-hydroxpyridine-0.70View
222-Amino-4-chloro-6-methylpyrimidine-0.47View
233,3-Dimethyl-2-butanone-1.44View
24Toluene-0.50View
25Carbon tetrachloride-0.02View
262-Chloro-4-methylaniline0.18View
272,3,4,5,6,-Pentafluoroaniline0.20View
28n-Propylsulfide0.00View
292,3-Benzofuran-0.11View
304-Xylene0.12View
313-Methylindole0.37View
32Methyl-4-chlorobenzoate0.42View
333-Benzyloxyaniline0.88View
34Butyl sulfide1.04View
351-Bromohexane0.94View
36XanthoneNTASView
372,3,4-Trichloroaniline1.35View
381,2,4-Trichlorobenzene1.08View
39Flavone1.41View
40AcenphtheneNTASView
411-Bromoheptane1.49View
421-Bromooctane1.87View
43Triphenyl phosphate1.81View
442,2'-Methylenebis(3,4,6-trichlorophenol)3.04View
45n-Vinylcarbazole2.24View
462-(2-Aminoethyl)pyridine-0.74View
47Triethanolamine-1.75View
48Diethanolamine-1.03View
491-Amino-2-propanol-0.93View
501-Methylpiperazine-0.96View
511-(2-Aminioethyl)piperazine-0.79View
521,3-Diaminopropane-0.70View
531,4-Bis(3-aminopropyl)piperazine-0.66View
541,2-Diaminopropane-0.56View
552-Butanone oxime-1.07View
563-Chloro-1-propanol-1.40View
572,4,5-Trimethyloxazole-1.01View
582-Aminobenzamide-0.87View
591-Chloro-2-propanol-1.49View
602,2,2-Trichloroethanol-0.46View
612,2-Dichloroacetamide-0.98View
62Acetaldoxime-0.89View
632-Acetyl-1-Methylpyrrole-0.69View
642,4-Dichlorobenzamide-0.36View
652-Chloroethanol-1.42View
662,3-Dibromopropanol-0.49View
67Triphenylphosphine oxide0.77View
68Methyl-4-chloro-2-nitrobenzoate0.82View
69γ-Decanolactone0.49View
702-Chloro-6-methylbenzonitrile0.46View
712',4'-Dichloroacetophenone0.62View
723,5-Dibromo-4-hydroxybenzonitrile1.16View
733-Bromothiophene-0.04View
744-Dimethylaminocinnamaldehyde0.52View
752,4,5-Tribromoimidazole1.43View
76Phenyl-4-Aminosalicylate1.41View
77Chloroacetonitrile0.85View
784,6-Dimethyl-2-hydroxybenzaldehyde0.62View
794-Nitrophenyl phenyl ether1.58View
802',3',4'-Trichloroacetophenone1.34View
81Malononitrile0.22View
821-Benzoylacetone0.57View
835-Bromosalicylaldehyde1.11View
845-Chlorosalicylaldehyde1.01View
85Diethyl chloromalonate0.63View
862,2'-Methylenebis(4-chlorophenol)3.09View
871,3-Dichloro-4,6-dinitrobenzene2.57View
88Lauryl acrylateNTASView
89AnthraquinoneNTASView
903,3-Dimethylglutaric acid-0.66View
91Propionic acid, sodium salt-1.45View
92Benzoic acid, sodium salt-0.92View
93Dimethyl aminoterephthalateNTASView
94Dimethyl nitroterephthalate0.43View
95Dibutyl succinate0.51View
96Dibutyl isophthalate1.44View
97Di-n-butyl terephthalateNTASView
98Diphenyl phthalateNTASView
991,5-Hexadien-3-ol0.25View
1002,4,6-Triiodophenol2.67View

Bibliography

  1. Sinks, G. D.; Schultz, T. W. Correlation of Tetrahymena and Pimephales Toxicity: Evaluation of 100 Additional Compounds. Environ. Toxicol. Chem. 2001, 20, 917–921. http://dx.doi.org/10.1002/etc.5620200429

  2. Schultz, T. W. TETRATOX: Tetrahymena pyriformis population growth impairment endpoint - a surrogate for fish lethality. Toxicol. Mech. Meth. 1997, 7, 289–309. http://dx.doi.org/10.1080/105172397243079