85 compounds | Property logK: HPLC chromatographic retention index on immobilized albumin [mM]
| ID | Name | logK | Details |
|---|---|---|---|
| 1 | 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)- | 0.21 | View |
| 2 | glibenclamide | 0.68 | View |
| 3 | Sumatriptan i | -0.81 | View |
| 4 | Acetamide, N-(4-hydroxyphenyl)- i | -0.05 | View |
| 5 | Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- | 0.49 | View |
| 6 | Pindolol | -0.13 | View |
| 7 | (2S)-1-(isopropylamino)-3-{2-[(1E)-prop-1-en-1-yl]phenoxy}propan-2-ol i | 0.04 | View |
| 8 | Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)- | -0.23 | View |
| 9 | Triflupromazine | 1.05 | View |
| 10 | Cephalexin | -1.11 | View |
| 11 | 4H-1-Benzopyran-2-carboxylic acid, 5,5'-[(2-hydroxy-1,3-propanediyl)bis(oxy)]bis[4-oxo- i | -1.07 | View |
| 12 | 5-Fluorocytosine | -1.11 | View |
| 13 | (2S)-2-(3-benzoylphenyl)propanoic acid | 0.03 | View |
| 14 | Naproxen | 0.25 | View |
| 15 | clotrimazole | 1.34 | View |
| 16 | (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol | -0.33 | View |
| 17 | novobiocin | 0.35 | View |
| 18 | Thymidine, 3'-azido-3'-deoxy- | -1.02 | View |
| 19 | Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-.beta.-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)- | -0.49 | View |
| 20 | Labetalol | 0.14 | View |
| 21 | Metoprolol | -0.29 | View |
| 22 | Acebutolol | -0.21 | View |
| 23 | Sotalol | -0.44 | View |
| 24 | Clonidine | -0.13 | View |
| 25 | Nadolol | -0.4 | View |
| 26 | Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)- | -0.4 | View |
| 27 | (9beta,11alpha,13alpha,14beta,17alpha)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione | -0.4 | View |
| 28 | (8alpha,9beta,13alpha,14beta,17alpha)-estra-1,3,5(10)-triene-3,17-diol | 0.68 | View |
| 29 | 4-butyl-1,2-diphenylpyrazolidine-3,5-dione | 0.19 | View |
| 30 | 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl- | 0.61 | View |
| 31 | Benzoic acid, 2-(acetyloxy)- | -1.39 | View |
| 32 | 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine i | -0.75 | View |
| 33 | 4(1H)-Pyrimidinone, 2,3-dihydro-6-propyl-2-thioxo- i | -0.44 | View |
| 34 | Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)- | 0.52 | View |
| 35 | 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl- | 0.47 | View |
| 36 | Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)- | -0.13 | View |
| 37 | 2H-Benzimidazol-2-one, 1-[1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro- | 0.43 | View |
| 38 | (6R,7R)-3-{[(aminocarbonyl)oxy]methyl}-7-({(2E)-2-furan-2-yl-2-[(methyloxy)imino]acetyl}amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | -1.33 | View |
| 39 | Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]- | -0.46 | View |
| 40 | 2,4-Imidazolidinedione, 5,5-diphenyl- | 0 | View |
| 41 | Androst-4-en-3-one, 17-hydroxy-, (17.beta.)- | 0.74 | View |
| 42 | promazine | 0.92 | View |
| 43 | 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide | -0.42 | View |
| 44 | N-{4-[[(2,4-diaminopteridin-6-yl)methyl](methyl)amino]benzoyl}-D-glutamic acid | -0.77 | View |
| 45 | 2-(diethylamino)ethyl 4-aminobenzoate | -0.19 | View |
| 46 | Benzoic acid, 2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]- | 0.56 | View |
| 47 | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)- | -0.08 | View |
| 48 | Terazosin | -0.16 | View |
| 49 | Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester | 0.27 | View |
| 50 | N-[(butylamino)carbonyl]-4-methylbenzenesulfonamide i | -0.56 | View |
| 51 | Ketoconazole | 0.84 | View |
| 52 | Ranitidine | -0.1 | View |
| 53 | salicylic acid | -0.66 | View |
| 54 | Norfloxacin | 0.14 | View |
| 55 | Card-20(22)-enolide, 3-[(O-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-O-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl-(1.fwdarw.4)-2,6-dideoxy-.beta.-D-ribo-hexopyranosyl)oxy]-14-hydroxy-, (3.beta.,5.beta.)- | 0.13 | View |
| 56 | L-Tryptophan | -0.78 | View |
| 57 | 2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]- | -0.26 | View |
| 58 | 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)- | -0.04 | View |
| 59 | 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo- | 0.14 | View |
| 60 | (6beta,9beta,11alpha,13alpha,14beta,17alpha)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione | -0.22 | View |
| 61 | Lamotrigine | -0.13 | View |
| 62 | 4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one | 1.04 | View |
| 63 | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-, (2S,5R,6R)- | -0.69 | View |
| 64 | Acrivastine | -0.02 | View |
| 65 | Terbinafine | 1.17 | View |
| 66 | Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]- | -0.44 | View |
| 67 | 2-(dimethylamino)ethyl 4-(butylamino)benzoate | 0.32 | View |
| 68 | Ondansetron | 0.37 | View |
| 69 | Benzenesulfonamide, N-[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]-4-methyl- | -0.42 | View |
| 70 | Prazosin | 0.06 | View |
| 71 | Amoxicillin | -1.21 | View |
| 72 | Bumetanide | -0.03 | View |
| 73 | Atenolol | -0.48 | View |
| 74 | 5H-dibenzo[b,f]azepine-5-carboxamide | -0.1 | View |
| 75 | 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl- | 0.75 | View |
| 76 | 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl- | 1.1 | View |
| 77 | (1R,2R,4S,5S,7R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate | -0.34 | View |
| 78 | Propranolol | 0.28 | View |
| 79 | Cinchonan-9-ol, 6'-methoxy-, (9S)- | 0.44 | View |
| 80 | (13alpha)-pregn-4-ene-3,20-dione | 0.59 | View |
| 81 | 1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione | -0.92 | View |
| 82 | 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl- | -0.69 | View |
| 83 | oxprenolol i | -0.22 | View |
| 84 | Cefuroxime axetil i | -0.15 | View |
| 85 | 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- | 0.14 | View |
Colmenarejo, G.; Alvarez-Pedraglio, A.; Lavandera, J.-L. Cheminformatic Models To Predict Binding Affinities to Human Serum Albumin. Journal of Medicinal Chemistry 2001, 44, 4370–4378. http://dx.doi.org/10.1021/jm010960b