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Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. Eur. J. Pharm. Sci. 2018, 123, 429-440.

238 compounds | Property logPo: Logarithmic intrinsic membrane permeability [log(cm/s)]

ID Name logPo Details
M001 Aciclovir -7.84 View
M002 Acitretin -1.46 View
M003 Allopurinol -6.9 View
M004 Ambroxol -2.55 View
M005 Aminophenazone -4.52 View
M006 Amitriptyline -2.22 View
M007 Amoxapine -3.23 View
M008 Antipyrine -5.97 View
M009 Astemizole -3 View
M010 Azelastine -1.64 View
M011 Beclomethasone dipropionate -5.49 View
M012 Benzbromarone -0.93 View
M013 Benzoic acid -3.18 View
M014 Betahistine -5.38 View
M015 Betaxolol -3.3 View
M016 Bicalutamide -5.06 View
M017 Bisacodyl -4.18 View
M018 Bisoprolol -4.16 View
M019 Budesonide -4.8 View
M020 Caffeine -5.56 View
M021 Carbadox -7.27 View
M022 Carbamazepine -5.12 View
M023 Carvedilol -3.84 View
M024 Cefadroxil -7.01 View
M025 Chloramphenicol -7.04 View
M026 Chlormadinone acetate -4.2 View
M027 Chloroquine -3.49 View
M028 Chlorphenamine -2.03 View
M029 Chlorpromazine -2.25 View
M030 Cinoxacin -6.72 View
M031 Ciprofloxacin -6.86 View
M032 Citalopram -1.69 View
M033 Clomipramine -3.39 View
M034 Clonidine -5.09 View
M035 Clozapine -2.78 View
M036 Cromoglicic acid -6.4 View
M037 Danofloxacin -6.82 View
M038 Dapsone -7.07 View
M039 Desipramine -1.46 View
M040 Dexamethasone -7.14 View
M041 Diclofenac -2.45 View
M042 Dicloxacillin -5.63 View
M043 Difloxacin -5.81 View
M044 Diflunisal -2.39 View
M045 Dihydroergotamine -5.92 View
M046 Diltiazem -3.76 View
M047 Dimetindene -4.4 View
M048 Disopyramide -3.36 View
M049 Dolasetron -5.88 View
M050 Domperidone -5.37 View
M051 Doxazosin -5.09 View
M052 Doxepin -1.72 View
M053 Enoxacin -7.51 View
M054 Enrofloxacin -6.43 View
M055 Ethinyl estradiol -4.36 View
M056 Etoricoxib -4.03 View
M057 Famotidine -8.31 View
M058 Fenoterol -6.75 View
M059 Fluconazole -6.5 View
M060 Flumequine -5.35 View
M061 Fluorescein -5.51 View
M062 Flutamide -4.2 View
M063 Fluvoxamine -3.21 View
M064 Furosemide -6.68 View
M065 Gemfibrozil -0.19 View
M066 Guanabenz -5.75 View
M067 Haloperidol -2.48 View
M068 Hydralazine -5.93 View
M069 Hydrochlorothiazide -8.47 View
M070 Hydroxychloroquine -5.28 View
M071 Imipramine -1.86 View
M072 Indomethacin -3.24 View
M073 Iopromide -7.13 View
M074 Irbesartan -4.65 View
M075 Isoniazid -6.66 View
M076 Isradipine -4.5 View
M077 Ketoconazole -4.14 View
M078 Ketoprofen -3.38 View
M079 Ketotifen -3.13 View
M080 Labetalol -6.59 View
M081 Lamivudine -7.2 View
M082 Lamotrigine -6.58 View
M083 Lidocaine -3.18 View
M084 Linezolid -7.03 View
M085 Lomefloxacin -7.32 View
M086 Marbofloxacin -6.74 View
M087 Mazipredone -6.85 View
M088 Medroxyprogesterone acetate -5.52 View
M089 Methylprednisolone -6.99 View
M090 Metoclopramide -4.24 View
M091 Metoprolol -4.13 View
M092 Metronidazole -7 View
M093 Metyrapone -4.24 View
M094 Midazolam -3.39 View
M095 Nafcillin -5.96 View
M096 Naloxone -4.66 View
M097 Naproxen -3.31 View
M098 Naratriptan -6.3 View
M099 Nevirapine -4.88 View
M100 Nicotinamide -6.45 View
M101 Nicotine -3.74 View
M102 Norfloxacin -7.51 View
M103 Ofloxacin -7.39 View
M104 Olaquindox -7.59 View
M105 Omeprazole -5.4 View
M106 Ondansetron -5.28 View
M107 Orbifloxacin -7.22 View
M108 Oxacillin -5.78 View
M109 Oxcarbazepine -5.55 View
M110 Oxprenolol -3.58 View
M111 Pantoprazole -5.84 View
M112 Papaverine -3.96 View
M113 Paroxetine -2.12 View
M114 Pentamidine -4.64 View
M115 Pentoxifylline -6.02 View
M116 Perphenazine -3.17 View
M117 Pheniramine -2.25 View
M118 Phenylbutazone -1.63 View
M119 Pindolol -5.69 View
M120 Pitofenone -3.51 View
M121 Prednisolone -7.41 View
M122 Prednisone -6.7 View
M123 Procaine -4.24 View
M124 Promethazine -2.63 View
M125 Propafenone -2.37 View
M126 Propofol -4.45 View
M127 Propranolol -2.16 View
M128 Pyrazinamide -6.26 View
M129 Quetiapine -3.88 View
M130 Quinine -3.63 View
M131 Rabeprazole -5.19 View
M132 Salicylic acid -3.27 View
M133 Sarafloxacin -7.14 View
M134 Sulfacetamide -7.33 View
M135 Sulfachloropyridazine -7.16 View
M136 Sulfadiazine -7.32 View
M137 Sulfadimethoxine -6.13 View
M138 Sulfadoxine -6.35 View
M139 Sulfaguanidine -7.3 View
M140 Sulfamerazine -7.2 View
M141 Sulfamethazine -6.97 View
M142 Sulfamethizole -7.3 View
M143 Sulfamethoxazole -6.83 View
M144 Sulfamethoxypyridazine -6.85 View
M145 Sulfamonomethoxine -6.78 View
M146 Sulfamoxole -7.27 View
M147 Sulfanilamide -7.3 View
M148 Sulfapyridine -7.2 View
M149 Sulfaquinoxaline -6.57 View
M150 Sulfathiazole -7.36 View
M151 Sulfisoxazole -6.73 View
M152 Sulindac -5.23 View
M153 Zalcitabine -7.18 View
M154 Zaleplon -5.41 View
M155 Tacrine -3.65 View
M156 Tenidap -3.33 View
M157 Theobromine -7.27 View
M158 Theophylline -7.32 View
M159 Thiabendazole -4.21 View
M160 Thiamphenicol -6.74 View
M161 Thiethylperazine -5.03 View
M162 Thioridazine -2.1 View
M163 Tiagabine -5.94 View
M164 Timolol -4.1 View
M165 Tinidazole -6.39 View
M166 Tizanidine -5.79 View
M167 Tofisopam -4.59 View
M168 Tolbutamide -4.12 View
M169 Tolperisone -2.47 View
M170 Tolterodine -1.45 View
M171 Tramadol -1.85 View
M172 Trazodone -3.53 View
M173 Triamcinolone -7.29 View
M174 Trimethoprim -6.76 View
M175 Tropisetron -4.89 View
M176 Valsartan -5.47 View
M177 Warfarin -3.36 View
M178 Verapamil -1.73 View
E01 8-hydroxyquinoline -3.95 View
E02 Acebutolol -6.27 View
E03 Acetanilide -4.88 View
E04 Acrivastine -6.08 View
E05 Alfuzosin -5.81 View
E06 Alosetron -6.63 View
E07 Aminosalicylic acid -5.15 View
E08 Amodiaquine -3.3 View
E09 Bendroflumethiazide -6.2 View
E10 Benzocaine -4.89 View
E11 Brimonidine -6.92 View
E12 Capecitabine -7.36 View
E13 Chloropyramine -3.08 View
E14 Chlorzoxazone -4.42 View
E15 Chlorthalidone -7.14 View
E16 Ciclopirox -4.11 View
E17 Coumarin -3.94 View
E18 Cyclobenzaprine -2.77 View
E19 Cyproheptadine -2.56 View
E20 Deferiprone -6.57 View
E21 Dipyridamole -5.77 View
E22 Donepezil -2.73 View
E23 Flupirtine -2.82 View
E24 Galantamine -3.84 View
E25 Granisetron -3.83 View
E26 Hesperetin -5.52 View
E27 Hydrocortisone -5.49 View
E28 Isoxepac -3.23 View
E29 Levofloxacin -6.98 View
E30 Levosimendan -6.4 View
E31 Loxapine -3.91 View
E32 Melatonin -6.01 View
E33 Menadione -3.79 View
E34 Mepivacaine -4.24 View
E35 Minoxidil -6.01 View
E36 Mycophenolate mofetil -4.47 View
E37 Nilvadipine -5.76 View
E38 Nizatidine -5.83 View
E39 Nitrofurantoin -6.4 View
E40 Oxybuprocaine -3.39 View
E41 Phenazopyridine -5.13 View
E42 Phenol -4.04 View
E43 Physostigmine -4.2 View
E44 Prilocaine -4.73 View
E45 Primaquine -2.79 View
E46 Procainamide -5.69 View
E47 Procarbazine -5.29 View
E48 Proparacaine -2.9 View
E49 Protionamide -4.9 View
E50 Pyridoxal -6.68 View
E51 Salicylamide -5.02 View
E52 Succinylsulfathiazole -6.4 View
E53 Sulpiride -5.87 View
E54 Zolmitriptan -4.99 View
E55 Tamsulosin -6.41 View
E56 Tolmetin -4.4 View
E57 Trichlormethiazide -6.66 View
E58 Tripelennamine -2.88 View
E59 Vardenafil -3.02 View
E60 Yohimbine -4.44 View

Bibliography

  1. Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. European Journal of Pharmaceutical Sciences 2018, 123, 429–440. http://dx.doi.org/10.1016/j.ejps.2018.07.014