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Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. Eur. J. Pharm. Sci. 2018, 123, 429-440.

238 compounds | Property logPe_pH7.4: Logarithmic effective membrane permeability at pH 7.4 [log(cm/s)]

ID Name logPe_pH7.4 Details
M001 Aciclovir -7.92 View
M002 Acitretin -5.24 View
M003 Allopurinol -6.87 View
M004 Ambroxol -4.56 View
M005 Aminophenazone -4.95 View
M006 Amitriptyline -4.91 View
M007 Amoxapine -4.55 View
M008 Antipyrine -5.95 View
M009 Astemizole -4.52 View
M010 Azelastine -4.5 View
M011 Beclomethasone dipropionate -5.51 View
M012 Benzbromarone -4.44 View
M013 Benzoic acid -6.57 View
M014 Betahistine -6.77 View
M015 Betaxolol -5.31 View
M016 Bicalutamide -5.11 View
M017 Bisacodyl -4.45 View
M018 Bisoprolol -6.3 View
M019 Budesonide -4.91 View
M020 Caffeine -5.58 View
M021 Carbadox -7.3 View
M022 Carbamazepine -5.15 View
M023 Carvedilol -5.1 View
M024 Cefadroxil -7.06 View
M025 Chloramphenicol -6.98 View
M026 Chlormadinone acetate -4.08 View
M027 Chloroquine -6.19 View
M028 Chlorphenamine -4.75 View
M029 Chlorpromazine -4.92 View
M030 Cinoxacin -7.5 View
M031 Ciprofloxacin -7.2 View
M032 Citalopram -4.43 View
M033 Clomipramine -5.4 View
M034 Clonidine -5.83 View
M035 Clozapine -4.33 View
M036 Cromoglicic acid -7.93 View
M037 Danofloxacin -7.31 View
M038 Dapsone -7.06 View
M039 Desipramine -4.56 View
M040 Dexamethasone -7.15 View
M041 Diclofenac -5.86 View
M042 Dicloxacillin -6.62 View
M043 Difloxacin -6.03 View
M044 Diflunisal -6.92 View
M045 Dihydroergotamine -6.08 View
M046 Diltiazem -4.63 View
M047 Dimetindene -4.71 View
M048 Disopyramide -6.24 View
M049 Dolasetron -5.75 View
M050 Domperidone -5.58 View
M051 Doxazosin -5.34 View
M052 Doxepin -4.41 View
M053 Enoxacin -7.56 View
M054 Enrofloxacin -6.78 View
M055 Ethinyl estradiol -4.41 View
M056 Etoricoxib -4.5 View
M057 Famotidine -8.53 View
M058 Fenoterol -6.84 View
M059 Fluconazole -6.42 View
M060 Flumequine -6.01 View
M061 Fluorescein -7.14 View
M062 Flutamide -4.13 View
M063 Fluvoxamine -4.89 View
M064 Furosemide -7.24 View
M065 Gemfibrozil -4.46 View
M066 Guanabenz -6.35 View
M067 Haloperidol -4.49 View
M068 Hydralazine -6.01 View
M069 Hydrochlorothiazide -8.51 View
M070 Hydroxychloroquine -7.52 View
M071 Imipramine -4.59 View
M072 Indomethacin -6.2 View
M073 Iopromide -7.1 View
M074 Irbesartan -7.03 View
M075 Isoniazid -6.73 View
M076 Isradipine -4.51 View
M077 Ketoconazole -5 View
M078 Ketoprofen -6.78 View
M079 Ketotifen -4.49 View
M080 Labetalol -6.9 View
M081 Lamivudine -7.2 View
M082 Lamotrigine -6.69 View
M083 Lidocaine -4.15 View
M084 Linezolid -7.11 View
M085 Lomefloxacin -7.34 View
M086 Marbofloxacin -7.6 View
M087 Mazipredone -6.97 View
M088 Medroxyprogesterone acetate -5.58 View
M089 Methylprednisolone -6.99 View
M090 Metoclopramide -6.55 View
M091 Metoprolol -6.29 View
M092 Metronidazole -7 View
M093 Metyrapone -4.44 View
M094 Midazolam -4.57 View
M095 Nafcillin -7.03 View
M096 Naloxone -5.33 View
M097 Naproxen -6.47 View
M098 Naratriptan -6.77 View
M099 Nevirapine -4.95 View
M100 Nicotinamide -6.53 View
M101 Nicotine -4.79 View
M102 Norfloxacin -7.57 View
M103 Ofloxacin -7.47 View
M104 Olaquindox -7.49 View
M105 Omeprazole -5.59 View
M106 Ondansetron -5.86 View
M107 Orbifloxacin -7.25 View
M108 Oxacillin -6.73 View
M109 Oxcarbazepine -5.54 View
M110 Oxprenolol -5.78 View
M111 Pantoprazole -6.17 View
M112 Papaverine -4.48 View
M113 Paroxetine -4.57 View
M114 Pentamidine -7.11 View
M115 Pentoxifylline -6.01 View
M116 Perphenazine -4.64 View
M117 Pheniramine -4.99 View
M118 Phenylbutazone -4.85 View
M119 Pindolol -6.7 View
M120 Pitofenone -4.47 View
M121 Prednisolone -7.45 View
M122 Prednisone -6.77 View
M123 Procaine -5.62 View
M124 Promethazine -4.75 View
M125 Propafenone -4.84 View
M126 Propofol -4.42 View
M127 Propranolol -4.9 View
M128 Pyrazinamide -6.27 View
M129 Quetiapine -4.49 View
M130 Quinine -5.35 View
M131 Rabeprazole -5.34 View
M132 Salicylic acid -7.22 View
M133 Sarafloxacin -7.28 View
M134 Sulfacetamide -7.4 View
M135 Sulfachloropyridazine -7.42 View
M136 Sulfadiazine -7.39 View
M137 Sulfadimethoxine -7.05 View
M138 Sulfadoxine -7.27 View
M139 Sulfaguanidine -7.3 View
M140 Sulfamerazine -7.31 View
M141 Sulfamethazine -7.07 View
M142 Sulfamethizole -7.36 View
M143 Sulfamethoxazole -7.28 View
M144 Sulfamethoxypyridazine -6.96 View
M145 Sulfamonomethoxine -7.37 View
M146 Sulfamoxole -7.34 View
M147 Sulfanilamide -7.35 View
M148 Sulfapyridine -7.26 View
M149 Sulfaquinoxaline -6.95 View
M150 Sulfathiazole -7.39 View
M151 Sulfisoxazole -7.41 View
M152 Sulindac -6.91 View
M153 Zalcitabine -7.19 View
M154 Zaleplon -5.47 View
M155 Tacrine -6.06 View
M156 Tenidap -5.95 View
M157 Theobromine -7.34 View
M158 Theophylline -7.46 View
M159 Thiabendazole -4.65 View
M160 Thiamphenicol -6.72 View
M161 Thiethylperazine -5.67 View
M162 Thioridazine -5.23 View
M163 Tiagabine -5.94 View
M164 Timolol -6.23 View
M165 Tinidazole -6.38 View
M166 Tizanidine -6.08 View
M167 Tofisopam -4.59 View
M168 Tolbutamide -6.33 View
M169 Tolperisone -4.29 View
M170 Tolterodine -4.63 View
M171 Tramadol -4.51 View
M172 Trazodone -4.5 View
M173 Triamcinolone -7.31 View
M174 Trimethoprim -6.91 View
M175 Tropisetron -6.83 View
M176 Valsartan -7.67 View
M177 Warfarin -5.96 View
M178 Verapamil -4.4 View
E01 8-hydroxyquinoline -4.64 View
E02 Acebutolol -7.38 View
E03 Acetanilide -4.99 View
E04 Acrivastine -6.12 View
E05 Alfuzosin -6.11 View
E06 Alosetron -6.72 View
E07 Aminosalicylic acid -7.18 View
E08 Amodiaquine -4.69 View
E09 Bendroflumethiazide -6.19 View
E10 Benzocaine -4.95 View
E11 Brimonidine -7.15 View
E12 Capecitabine -7.38 View
E13 Chloropyramine -4.53 View
E14 Chlorzoxazone -4.96 View
E15 Chlorthalidone -7.17 View
E16 Ciclopirox -5.15 View
E17 Coumarin -4.01 View
E18 Cyclobenzaprine -4.56 View
E19 Cyproheptadine -4.46 View
E20 Deferiprone -6.52 View
E21 Dipyridamole -5.95 View
E22 Donepezil -4.58 View
E23 Flupirtine -4.87 View
E24 Galantamine -5.29 View
E25 Granisetron -5.52 View
E26 Hesperetin -6.06 View
E27 Hydrocortisone -5.39 View
E28 Isoxepac -6.51 View
E29 Levofloxacin -7 View
E30 Levosimendan -6.84 View
E31 Loxapine -4.72 View
E32 Melatonin -6.01 View
E33 Menadione -3.79 View
E34 Mepivacaine -4.96 View
E35 Minoxidil -6.26 View
E36 Mycophenolate mofetil -5.19 View
E37 Nilvadipine -5.81 View
E38 Nizatidine -5.94 View
E39 Nitrofurantoin -7 View
E40 Oxybuprocaine -5.14 View
E41 Phenazopyridine -5.12 View
E42 Phenol -4.04 View
E43 Physostigmine -5.23 View
E44 Prilocaine -5.38 View
E45 Primaquine -5.62 View
E46 Procainamide -6.44 View
E47 Procarbazine -5.39 View
E48 Proparacaine -5.33 View
E49 Protionamide -4.99 View
E50 Pyridoxal -6.69 View
E51 Salicylamide -5.17 View
E52 Succinylsulfathiazole -7.89 View
E53 Sulpiride -7.08 View
E54 Zolmitriptan -7.13 View
E55 Tamsulosin -7.37 View
E56 Tolmetin -7.3 View
E57 Trichlormethiazide -7.03 View
E58 Tripelennamine -4.38 View
E59 Vardenafil -5.22 View
E60 Yohimbine -5.18 View

Bibliography

  1. Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. European Journal of Pharmaceutical Sciences 2018, 123, 429–440. http://dx.doi.org/10.1016/j.ejps.2018.07.014