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Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. Eur. J. Pharm. Sci. 2018, 123, 429-440.

238 compounds | Property logPe_pH5: Logarithmic effective membrane permeability at pH 5 [log(cm/s)]

ID Name logPe_pH5 Details
M001 Aciclovir -7.91 View
M002 Acitretin -4.88 View
M003 Allopurinol -6.97 View
M004 Ambroxol -6.83 View
M005 Aminophenazone -5.3 View
M006 Amitriptyline -6.71 View
M007 Amoxapine -6.69 View
M008 Antipyrine -5.95 View
M009 Astemizole -6.77 View
M010 Azelastine -6.46 View
M011 Beclomethasone dipropionate -5.52 View
M012 Benzbromarone -4.17 View
M013 Benzoic acid -4.48 View
M014 Betahistine -7 View
M015 Betaxolol -6.5 View
M016 Bicalutamide -5.13 View
M017 Bisacodyl -4.61 View
M018 Bisoprolol -7.12 View
M019 Budesonide -4.86 View
M020 Caffeine -5.54 View
M021 Carbadox -7.2 View
M022 Carbamazepine -5.17 View
M023 Carvedilol -6.73 View
M024 Cefadroxil -7.08 View
M025 Chloramphenicol -7.05 View
M026 Chlormadinone acetate -4.24 View
M027 Chloroquine -8.47 View
M028 Chlorphenamine -6.37 View
M029 Chlorpromazine -6.95 View
M030 Cinoxacin -6.92 View
M031 Ciprofloxacin -7.24 View
M032 Citalopram -5.89 View
M033 Clomipramine -6.92 View
M034 Clonidine -7.01 View
M035 Clozapine -5.69 View
M036 Cromoglicic acid -7.76 View
M037 Danofloxacin -7.27 View
M038 Dapsone -7.06 View
M039 Desipramine -6.74 View
M040 Dexamethasone -7.14 View
M041 Diclofenac -4.49 View
M042 Dicloxacillin -6.64 View
M043 Difloxacin -6.86 View
M044 Diflunisal -4.61 View
M045 Dihydroergotamine -7.33 View
M046 Diltiazem -6.77 View
M047 Dimetindene -6.75 View
M048 Disopyramide -6.66 View
M049 Dolasetron -6.79 View
M050 Domperidone -6.81 View
M051 Doxazosin -7.08 View
M052 Doxepin -6.17 View
M053 Enoxacin -7.55 View
M054 Enrofloxacin -7.29 View
M055 Ethinyl estradiol -4.44 View
M056 Etoricoxib -4.57 View
M057 Famotidine -8.68 View
M058 Fenoterol -7.07 View
M059 Fluconazole -6.5 View
M060 Flumequine -5.46 View
M061 Fluorescein -6.12 View
M062 Flutamide -4.25 View
M063 Fluvoxamine -6.94 View
M064 Furosemide -7 View
M065 Gemfibrozil -4.07 View
M066 Guanabenz -7.55 View
M067 Haloperidol -6.1 View
M068 Hydralazine -7.1 View
M069 Hydrochlorothiazide -8.41 View
M070 Hydroxychloroquine -8.27 View
M071 Imipramine -6.39 View
M072 Indomethacin -4.76 View
M073 Iopromide -7.26 View
M074 Irbesartan -5.38 View
M075 Isoniazid -6.85 View
M076 Isradipine -4.48 View
M077 Ketoconazole -5.84 View
M078 Ketoprofen -4.82 View
M079 Ketotifen -6.55 View
M080 Labetalol -7.05 View
M081 Lamivudine -7.34 View
M082 Lamotrigine -7.07 View
M083 Lidocaine -6.13 View
M084 Linezolid -7.03 View
M085 Lomefloxacin -7.37 View
M086 Marbofloxacin -7.28 View
M087 Mazipredone -7.01 View
M088 Medroxyprogesterone acetate -5.52 View
M089 Methylprednisolone -7 View
M090 Metoclopramide -7.35 View
M091 Metoprolol -7.24 View
M092 Metronidazole -7 View
M093 Metyrapone -4.74 View
M094 Midazolam -4.84 View
M095 Nafcillin -6.77 View
M096 Naloxone -6.46 View
M097 Naproxen -4.82 View
M098 Naratriptan -6.77 View
M099 Nevirapine -4.98 View
M100 Nicotinamide -6.46 View
M101 Nicotine -6.88 View
M102 Norfloxacin -7.64 View
M103 Ofloxacin -7.56 View
M104 Olaquindox -7.52 View
M105 Omeprazole -5.52 View
M106 Ondansetron -7.71 View
M107 Orbifloxacin -7.1 View
M108 Oxacillin -6.61 View
M109 Oxcarbazepine -5.57 View
M110 Oxprenolol -7 View
M111 Pantoprazole -5.83 View
M112 Papaverine -5.4 View
M113 Paroxetine -6.56 View
M114 Pentamidine -7.15 View
M115 Pentoxifylline -5.99 View
M116 Perphenazine -6.2 View
M117 Pheniramine -6.44 View
M118 Phenylbutazone -4.62 View
M119 Pindolol -6.87 View
M120 Pitofenone -6.58 View
M121 Prednisolone -7.41 View
M122 Prednisone -6.74 View
M123 Procaine -7.17 View
M124 Promethazine -6.5 View
M125 Propafenone -6.58 View
M126 Propofol -4.49 View
M127 Propranolol -6.6 View
M128 Pyrazinamide -6.27 View
M129 Quetiapine -5.94 View
M130 Quinine -7.19 View
M131 Rabeprazole -5.61 View
M132 Salicylic acid -5.53 View
M133 Sarafloxacin -7.4 View
M134 Sulfacetamide -7.33 View
M135 Sulfachloropyridazine -7.21 View
M136 Sulfadiazine -7.34 View
M137 Sulfadimethoxine -6.19 View
M138 Sulfadoxine -6.43 View
M139 Sulfaguanidine -7.35 View
M140 Sulfamerazine -7.19 View
M141 Sulfamethazine -6.99 View
M142 Sulfamethizole -7.28 View
M143 Sulfamethoxazole -6.97 View
M144 Sulfamethoxypyridazine -6.81 View
M145 Sulfamonomethoxine -6.82 View
M146 Sulfamoxole -7.27 View
M147 Sulfanilamide -7.23 View
M148 Sulfapyridine -7.23 View
M149 Sulfaquinoxaline -6.63 View
M150 Sulfathiazole -7.28 View
M151 Sulfisoxazole -6.93 View
M152 Sulindac -6.01 View
M153 Zalcitabine -7.29 View
M154 Zaleplon -5.48 View
M155 Tacrine -7.78 View
M156 Tenidap -5.07 View
M157 Theobromine -7.23 View
M158 Theophylline -7.45 View
M159 Thiabendazole -4.71 View
M160 Thiamphenicol -6.76 View
M161 Thiethylperazine -7.09 View
M162 Thioridazine -6.85 View
M163 Tiagabine -6.08 View
M164 Timolol -6.96 View
M165 Tinidazole -6.47 View
M166 Tizanidine -7.85 View
M167 Tofisopam -4.59 View
M168 Tolbutamide -4.79 View
M169 Tolperisone -6.24 View
M170 Tolterodine -6.23 View
M171 Tramadol -6.34 View
M172 Trazodone -5.85 View
M173 Triamcinolone -7.27 View
M174 Trimethoprim -7.22 View
M175 Tropisetron -7.48 View
M176 Valsartan -5.99 View
M177 Warfarin -4.61 View
M178 Verapamil -5.8 View
E01 8-hydroxyquinoline -4.68 View
E02 Acebutolol -7.35 View
E03 Acetanilide -4.97 View
E04 Acrivastine -6.41 View
E05 Alfuzosin -6.82 View
E06 Alosetron -7.16 View
E07 Aminosalicylic acid -7.06 View
E08 Amodiaquine -6.89 View
E09 Bendroflumethiazide -6.31 View
E10 Benzocaine -4.9 View
E11 Brimonidine -7.23 View
E12 Capecitabine -7.32 View
E13 Chloropyramine -7.02 View
E14 Chlorzoxazone -4.65 View
E15 Chlorthalidone -7.06 View
E16 Ciclopirox -4.21 View
E17 Coumarin -3.99 View
E18 Cyclobenzaprine -6.19 View
E19 Cyproheptadine -6.42 View
E20 Deferiprone -6.77 View
E21 Dipyridamole -6.7 View
E22 Donepezil -6.81 View
E23 Flupirtine -5.44 View
E24 Galantamine -6.53 View
E25 Granisetron -7.72 View
E26 Hesperetin -5.36 View
E27 Hydrocortisone -5.6 View
E28 Isoxepac -5 View
E29 Levofloxacin -7.45 View
E30 Levosimendan -6.66 View
E31 Loxapine -6.62 View
E32 Melatonin -5.94 View
E33 Menadione -3.79 View
E34 Mepivacaine -6.41 View
E35 Minoxidil -6.21 View
E36 Mycophenolate mofetil -5.49 View
E37 Nilvadipine -5.87 View
E38 Nizatidine -6.99 View
E39 Nitrofurantoin -6.38 View
E40 Oxybuprocaine -6.74 View
E41 Phenazopyridine -5.65 View
E42 Phenol -4.1 View
E43 Physostigmine -6.69 View
E44 Prilocaine -6.76 View
E45 Primaquine -6.89 View
E46 Procainamide -7.06 View
E47 Procarbazine -5.72 View
E48 Proparacaine -7.1 View
E49 Protionamide -5.23 View
E50 Pyridoxal -6.93 View
E51 Salicylamide -5.05 View
E52 Succinylsulfathiazole -6.75 View
E53 Sulpiride -7.2 View
E54 Zolmitriptan -7.08 View
E55 Tamsulosin -7.44 View
E56 Tolmetin -5.95 View
E57 Trichlormethiazide -6.74 View
E58 Tripelennamine -6.84 View
E59 Vardenafil -7.01 View
E60 Yohimbine -6.89 View

Bibliography

  1. Oja, M.; Maran, U. pH-permeability profiles for drug substances: Experimental detection, comparison with human intestinal absorption and modelling. European Journal of Pharmaceutical Sciences 2018, 123, 429–440. http://dx.doi.org/10.1016/j.ejps.2018.07.014