71 compounds | Property pKi: Antiviral binding affinity equilibrium constant as p(Ki) [-log(mol/L)]
| ID | Name | pKi | Details |
|---|---|---|---|
| 1 | 6-Ethyl-6-(m-tolyl)-pyrrolo[1,2-d]pyrido[3,2-b][1,4]oxazepin-7(6H)-one i | 7.68 | View |
| 2 | 6-Ethyl-6-phenylpyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazepin-7(6H)-one i | 7.66 | View |
| 3 | 6-Ethyl-6-(2-thienyl)pyrrolo[2,1-d][1,5]benzoxazepin-7(6H)-one i | 7.52 | View |
| 4 | 6-Ethyl-6-(3-methoxyphenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7(6H)-one i | 7.22 | View |
| 5 | 6-ethyl-6-(3-methylphenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7-one i | 7.15 | View |
| 6 | 6-Ethyl-6-(2-thienyl)pyrido[3,2-b]pyrrolo[1,2-d][1,4]oxazepin-7(6H)-one i | 7.03 | View |
| 7 | 6-Ethyl-6-(3-fluorophenyl)pyrrolo[2,1-d][1,5]benzoxazepin-7(6H)-one i | 7 | View |
| 8 | 6-ethyl-6-phenylpyrrolo[2,1-d][1,5]benzoxazepin-7-one i | 6.72 | View |
| 9 | 5-Ethyl-5-p-tolyl-6-oxa-10b-aza-benzo[e]azulen-4-one i | 6.01 | View |
| 10 | 6-(3,5-Difluorophenyl)-6-ethylpyrrolo[2,1-d][1,5]benzoxazepin-7(6H)-one i | 5.82 | View |
| 11 | 1-(5-bromopyridin-2-yl)-3-[2-(7,9-difluoro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 7 | View |
| 12 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(4-oxo-4H-5,9,9b-triaza-cyclopenta[a]naphthalen-5-yl)-ethyl]-thiourea i | 6.95 | View |
| 13 | 1-(5-bromopyridin-2-yl)-3-[2-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.96 | View |
| 14 | 1-(5-bromopyridin-2-yl)-3-[2-(7-chloro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.81 | View |
| 15 | 1-(5-bromopyridin-2-yl)-3-[2-(6-fluoro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.78 | View |
| 16 | 1-(5-bromopyridin-2-yl)-3-[2-(9-fluoro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.52 | View |
| 17 | 1-(5-bromopyridin-2-yl)-3-[2-(4-oxoimidazo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.17 | View |
| 18 | 1-(5-bromopyridin-2-yl)-3-[2-(7-fluoro-4-oxopyrrolo[1,2-a]quinoxalin-5-yl)ethyl]thiourea i | 6.17 | View |
| 19 | 1-(5-bromopyridin-2-yl)-3-[2-(7-chloropyrrolo[1,2-a]quinoxalin-4-yl)oxyethyl]thiourea i | 6.96 | View |
| 20 | 1-(5-bromopyridin-2-yl)-3-[2-(6-fluoropyrrolo[1,2-a]quinoxalin-4-yl)oxyethyl]thiourea i | 6.65 | View |
| 21 | 1-(5-bromopyridin-2-yl)-3-[2-(7,8-dimethylpyrrolo[1,2-a]quinoxalin-4-yl)oxyethyl]thiourea i | 6.32 | View |
| 22 | N'-pyrrolo[1,2-a]quinoxalin-4-ylpyrazine-2-carbohydrazide i | 6.09 | View |
| 23 | 1-(5-bromopyridin-2-yl)-3-(pyrrolo[1,2-a]quinoxalin-4-ylamino)thiourea i | 5.72 | View |
| 24 | 1-(5-bromopyridin-2-yl)-3-(pyrrolo[1,2-a]quinoxalin-4-ylamino)urea i | 5.59 | View |
| 25 | N'-pyrrolo[1,2-a]quinoxalin-4-ylpyridine-2-carbohydrazide i | 5.39 | View |
| 26 | Efavirenz i | 6.87 | View |
| 27 | 1-(5-bromopyridin-2-yl)-3-[2-(5-oxopyrazolo[1,5-c]quinazolin-6-yl)ethyl]thiourea i | 6.67 | View |
| 28 | 3,5,8-trihydroxy-1H-quinolin-4-one i | 6.31 | View |
| 29 | 1-(5-bromopyridin-2-yl)-3-[2-(2-fluorophenyl)ethyl]thiourea i | 6.22 | View |
| 30 | Trovirdine i | 6.22 | View |
| 31 | 1-(5-bromopyridin-2-yl)-3-[(1R)-1-cyclohexylethyl]thiourea i | 5.96 | View |
| 32 | 1-(5-chloropyridin-2-yl)-3-[(1R)-1-cyclohexylethyl]thiourea i | 5.92 | View |
| 33 | N-[2-[4-[[3-(tert-butylamino)pyridin-2-yl]-methylamino]piperidine-1-carbonyl]-1H-indol-5-yl]methanesulfonamide i | 5.85 | View |
| 34 | N-[2-[4-[[3-(tert-butylamino)pyridin-2-yl]-ethylamino]piperidine-1-carbonyl]-1H-indol-5-yl]methanesulfonamide i | 5.83 | View |
| 35 | (Alkylamino)piperidine BHAP Analog 36 i | 5.73 | View |
| 36 | Nevirapine i | 5.05 | View |
| 37 | 1-[(1R)-1-cyclohexylethyl]-3-(1,3-thiazol-2-yl)thiourea i | 4.92 | View |
| 38 | bis[(4-methylphenyl)amino]-1,3,5-triazin-2-ol i | 4.26 | View |
| 39 | 2-N,4-N-bis(4-methylphenyl)-1,3,5-triazine-2,4,6-triamine i | 3.94 | View |
| 40 | [(2R,3R,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate i | 8.44 | View |
| 41 | [[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]phosphoryl]boron i | 7.35 | View |
| 42 | [[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxy-[[(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl]boron i | 7.34 | View |
| 43 | Stavudine triphosphate i | 7.25 | View |
| 44 | Thymidine 5'-triphosphate i | 7.21 | View |
| 45 | 3'-Fluorothymidine-5'-triphosphate i | 7.15 | View |
| 46 | [[[[(2R,3R,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]oxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]amino]phosphonic acid i | 7.06 | View |
| 47 | Zidovudine triphosphate i | 7.04 | View |
| 48 | [[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 7.03 | View |
| 49 | [[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl]boron i | 6.63 | View |
| 50 | [[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxy-[[(2S,5R)-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]phosphoryl]boron i | 6.36 | View |
| 51 | 2',3'-Dideoxyuridine-5'-triphosphate i | 6.26 | View |
| 52 | [[[[3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]-difluoromethyl]phosphonic acid i | 5.65 | View |
| 53 | [(2R,3R,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]oxy-N-[hydroxy(phosphonooxy)phosphoryl]phosphonamidic acid i | 5.62 | View |
| 54 | N-[hydroxy-[(2R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]oxyphosphoryl]-phosphonooxyphosphonamidic acid i | 4.82 | View |
| 55 | [[hydroxy-[[hydroxy-[(2R,3R,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]oxyphosphoryl]amino]phosphoryl]amino]phosphonic acid i | 4.72 | View |
| 56 | [(2R,3R,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]oxy-N-[hydroxy(phosphonooxy)phosphoryl]phosphonamidic acid i | 4.66 | View |
| 57 | [[4-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate i | 7.79 | View |
| 58 | 2',3'-Dideoxyadenosine triphosphate i | 7.69 | View |
| 59 | [[(1S,4R)-4-(2-amino-6-oxo-3H-purin-9-yl)cyclopent-2-en-1-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 7.47 | View |
| 60 | [[(4R)-4-(2-amino-6-oxo-3H-purin-9-yl)cyclopent-2-en-1-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate i | 7.43 | View |
| 61 | [[(2S,5R)-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 7.33 | View |
| 62 | [[[(2Z)-2-[(6-aminopurin-9-yl)methylidene]cyclopropyl]methoxy-hydroxyphosphoryl]-hydroxyphosphoryl]phosphonic acid i | 5.77 | View |
| 63 | [[[(2E)-2-[(6-aminopurin-9-yl)methylidene]cyclopropyl]methoxy-hydroxyphosphoryl]-hydroxyphosphoryl]phosphonic acid i | 4.28 | View |
| 64 | [[(2S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 7.64 | View |
| 65 | Zalcitabine i | 7.29 | View |
| 66 | Lamivudine Triphosphate i | 6.73 | View |
| 67 | [[(2S,5R)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate i | 6.3 | View |
| 68 | [[(2S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 6.5 | View |
| 69 | [[(2S,5R)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 5.75 | View |
| 70 | [[(2S,5R)-5-(6-amino-7-oxo-4H-imidazo[4,5-c]pyridin-3-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate i | 7.6 | View |
| 71 | [[(2S,5R)-5-(6-amino-4-oxo-5H-imidazo[4,5-c]pyridin-1-yl)oxolan-2-yl]methoxy-[[difluoro(phosphono)methyl]-hydroxyphosphoryl]oxyphosphoryl]boron i | 7.15 | View |