10967/142 - QDB Compounds

QsarDB Repository

Franke, R.; Gruska, A.; Giuliani, A.; Benigni, R. Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model. Carcinogenesis 2001, 22, 1561–1571.

64 compounds | Property Potency: Carcinogenic potency as log(MW/TD50) [log((mol/kg)/TD50)]

IDNamePotencyDetails
12-Naphthylamine31.812977View
2Benzidine30.701297View
32-Acetylaminofluorene31.316399View
4Isopropyl-N-(3-chlorophenyl)carbamate25.704177View
54,4'-Methylenebis(2-chloroaniline)30.374841View
6o-Toluidine i30.312155View
72-Biphenylamine hydrochloride i32.495717View
82,6-Dichloro-p-phenylenediamine29.243666View
94,4'-Methylenedianiline dihydrochloride i31.141457View
10Monuron29.438709View
114,4'-Oxydianiline30.013225View
122,6-Xylidine32.281568View
13o-Anthranilic acid27.651058View
14Acetamide, N-​[4-​(2-​chloroacetyl)​phenyl]​- i28.112443View
152-Chloro-p-phenylenediamine sulphate i27.574515View
162,4-Dimethoxyaniline hydrochloride i28.662278View
174-Nitroanthranilic acid28.565774View
184-Nitro-o-phenylenediamine27.846439View
19p-Phenylenediamine dihydrochloride i28.353338View
20N-Phenyl-p-phenylenediamine28.66891View
211-Phenyl-2-thiourea25.890942View
221,​4-​Benzenediamine, 2-​methyl-​, sulfate i28.312969View
233-Amino-4-ethoxyacetanilide32.078816View
243-Amino-9-ethylcarbazole i30.11006View
254-Amino-2-nitrophenol30.976417View
26Aniline hydrochloride i30.584329View
27o-Anisidine i29.845678View
28p-Chloroaniline hydrochloride i29.141363View
294-Chloro-m-phenylenediamine29.732037View
304-Chloro-o-phenylenediamine28.307538View
313-Chloro-p-toluidine29.108589View
32m-Cresidine29.533803View
33p-Cresidine30.795875View
34Dapsone i30.445915View
352,4-Diaminoanisole sulfate i29.752109View
362,4-Diaminotoluene i30.503514View
371,5-Naphthalenediamine30.291436View
383-Nitro-p-acetophenetide31.118461View
39Benzenamine, 2-​methoxy-​5-​nitro- i29.683528View
404,4'-Thiodianiline29.663216View
412,4,5-Trimethylaniline30.690156View
424-Aminobiphenyl31.384286View
432-Amino-5-nitrophenol28.043143View
442,4-Diaminophenol dihydrochloride i29.285568View
454-Acetylaminobiphenyl31.48436View
464'-Fluoro-4-aminodiphenyl30.717083View
474-Acetylamino-4'-fluorobiphenyl i30.859044View
48N-(2-Fluorenyl)-2,2,2-trifluoroacetamide31.720341View
494-Chloro-4'-aminodiphenyl ether i31.112002View
503,3'-Dichlorobenzidine29.702301View
51Acedapsone i30.202766View
52Phenacetin29.577049View
53o-Phenylenediamine dihydrochloride i29.376852View
543,3',4,4'-Tetraaminobiphenyl tetrahydrochloride i30.11309View
551,3-Benzenediamine, 2,4,5,6-tetrafluoro- i28.637859View
562,4,6-Trimethylanilinium chloride i31.811782View
57p-Toluidine hydrochloride i29.913306View
582-Amino-4-nitrophenol29.611704View
592,4,6-Trichloroaniline30.188203View
60m-Toluidine hydrochloride i28.157319View
613,3'-Dimethoxybenzidine dihydrochloride i29.946611View
62o-Toluidine dihydrochloride i30.278359View
63Chloramben30.64138View
644,4'-Methylenebis (2-methylaniline)30.956058View

Bibliography

  1. Franke, R.; Gruska, A.; Giuliani, A.; Benigni, R. Prediction of rodent carcinogenicity of aromatic amines: a quantitative structure-activity relationships model. Carcinogenesis 2001, 22, 1561–1571. http://dx.doi.org/10.1093/carcin/22.9.1561